基本信息
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职业迁徙
个人简介
We study the molecular architecture of the postsynaptic site of glutamatergic synapses in the mammalian brain. We use biochemical, cell biological and electrophysiological methods to investigate how various structural proteins anchor postsynaptic glutamate receptors. We investigate how postsynaptic signaling by calcium influx and by protein kinase A (PKA) and other kinases and phosphatases defines postsynaptic glutamate receptor trafficking and accumulation under physiological conditions as occurring during learning. We also study mechanisms underlying Alzheimer’s disease and PTSD.
Research Interests & Expertise
Molecular, cellular, and electrophysiological analysis synaptic transmission
Protein protein interactions and signaling within nano domains, super resolution imaging , single ion channel recording
研究兴趣
论文共 198 篇作者统计合作学者相似作者
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Chelsea A Crossley, Tamunotonye Omoluabi, Sarah E Torraville, Sarah Duraid,Aida Maziar, Zia Hasan,Vishaal Rajani,Kanae Ando,Johannes W Hell,Qi Yuan
Brain communicationsno. 2 (2024): fcae096-fcae096
EMBO reportsno. 3 (2024): 948-950
Nature neurosciencepp.1-2, (2024)
SCIENCE SIGNALINGno. 808 (2023)
biorxiv(2023)
Kyle E. Ireton, Xiaoming Xing,Karam Kim, Justin C. Weiner,Ariel A. Jacobi, Aarushi Grover,Molly Foote, Yusuke Ota,Robert Berman,Timothy Hanks,Johannes W. Hell
The Journal of neuroscience : the official journal of the Society for Neuroscienceno. 30 (2023): 5559-5573
PHYSIOLOGYno. S1 (2023)
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Proceedings of the National Academy of Sciences of the United States of Americano. 14 (2023)
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