基本信息
浏览量:346
职业迁徙
个人简介
The primary research focus of the lab is to understand aberrant transcriptional and epigenetic regulation of prostate cancer. We utilize high-throughput genomic techniques in combination with bioinformatics/statistical analysis to generate hypothetical concepts. We then test these hypotheses using traditional molecular or cellular biological approaches and examine the functional relevance of innovative mechanisms using in vitro cell line and in vivo mouse models. Transcription factors of particular interest to us include androgen receptor (AR), FoxA1, Polycomb group protein (EZH2), and the Ets family protein (ERG). Based on the genetics and epigenetics of the disease, we also pursue translational research to define diagnostic / prognostic biomarkers and to pursue novel therapeutics strategies for treating advanced prostate cancer.
研究兴趣
论文共 172 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Marina G. Ferrari, Alexis P. Jimenez-Uribe,Li Wang,Luke H. Hoeppner,Paari Murugan,Eunsil Hahm,Jindan Yu,Timothy M. Kuzel,Sergio A. Gradilone,Adrian P. Mansini
Oncogeneno. 7 (2024): 484-494
Marina G. Ferrari, Alexis P. Jimenez-Uribe,Li Wang,Luke H. Hoeppner,Paari Murugan,Eunsil Hahm,Jindan Yu,Timothy M. Kuzel,Sergio A. Gradilone,Adrian P. Mansini
ONCOGENEno. 7 (2024): 484-494
CANCER RESEARCHno. 11 (2023)
引用0浏览0引用
0
0
Christina S. Pichot,Constadina Arvanitis,Sean M. Hartig, Samuel A. Jensen, John Bechill, Saad Marzouk,Jindan Yu, Jeffrey A. Frost,Seth J. Corey
crossref(2023)
Guoan Chen,Xiaoju Wang,Jianjun Yu,Sooryanarayana Varambally,Jindan Yu,Dafydd G. Thomas,Mu-Yen Lin,Prakash Vishnu, Zhuwen Wang,Rui Wang, Jeff Fielhauer,Debashis Ghosh,
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn