Jie Zheng

基本信息

Career Trajectory

Bio

I am currently a professor at Shanghai Jiaotong University School of Medicine. My major research interest is on applying causal inference approaches such as Mendelian randomization to enhance our understanding for the genetic aetiology of complex human diseases. I am particularly interested in applying phenome-wide Mendelian randomization to molecular phenotypes, such as protein, gene expression and methylation to accelerate drug development. Email: Jie.Zheng@bristol.ac.uk

Research Interests

Papers共 186 篇Author StatisticsCo-AuthorSimilar Experts

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Kidney Multiome-Based Genetic Scorecard Reveals Convergent Coding and Regulatory Variants

Hongbo Liu,Amin Abedini,Eunji Ha, Ziyuan Ma, Xin Sheng,Bernhard Dumoulin,Chengxiang Qiu,Tamas Aranyi,Shen Li, Nicole Dittrich,Hua-Chang Chen,Ran Tao, Der-Cherng Tarng,Feng-Jen Hsieh,Shih-Ann Chen,Shun-Fa Yang, Mei-Yueh Lee,Pui-Yan Kwok,Jer-Yuarn Wu,Chien-Hsiun Chen,Atlas Khan,Nita A Limdi,Wei-Qi Wei,Theresa L Walunas,Elizabeth W Karlson,Eimear E Kenny,Yuan Luo,Leah Kottyan, John J Connolly,Gail P Jarvik,Chunhua Weng,Ning Shang,Joanne B Cole,Josep M Mercader,Ravi Mandla,Timothy D Majarian, Jose C Florez, Mary E Haas,Luca A Lotta,Regeneron Genetics Center‡, GHS-RGC DiscovEHR Collaboration§,Theodore G Drivas,Penn Medicine BioBank¶,Ha My T Vy,Girish N Nadkarni,Laura K Wiley, Melissa P Wilson,Christopher R Gignoux,Humaira Rasheed,Laurent F Thomas,Bjørn Olav Åsvold,Ben M Brumpton,Stein I Hallan,Kristian Hveem,Jie Zheng,Jacklyn N Hellwege,Matthew Zawistowski,Sebastian Zöllner,Nora Franceschini,Hailong Hu, Jianfu Zhou,Krzysztof Kiryluk,Marylyn D Ritchie,Matthew Palmer,Todd L Edwards,Benjamin F Voight,Adriana M Hung,Katalin Susztak,Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration,Penn Medicine BioBank

Science (New York, NY)（2025）

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Transcriptome-wide Mendelian Randomisation Exploring Dynamic CD4+ T Cell Gene Expression in Colorectal Cancer Development

Benedita Deslandes,Xueyan Wu,Matthew A Lee, Lucy J Goudswaard, Gareth W Jones,Andrea Gsur,Annika Lindblom,Shuji Ogino,Veronika Vymetalkova,Alicja Wolk,Anna H Wu, Jeroen R Huyghe,Ulrike Peters, Amanda I Phipps,Claire E Thomas,Rish K Pai, Robert C Grant, Daniel D Buchanan, James Yarmolinsky, Marc J Gunter,Jie Zheng,Emma Hazelwood,Emma E Vincent

medRxiv the preprint server for health sciences (2025)

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Circulating Short-Chain and Branched Short-Chain Fatty Acids and the Risk of Incident Type 2 Diabetes: Findings from the 4C Study

Shuangyuan Wang,Hong Lin, Xiaojing Jia, Yiting Lin, Chunyan Hu,Mian Li,Yu Xu,Min Xu,Jie Zheng,Xinjie Zhao,Yanli Li,Lulu Chen,Tianshu Zeng,Ruying Hu,Zhen Ye,Lixin Shi,Qing Su,Yuhong Chen,Xuefeng Yu,Li Yan,Tiange Wang,Zhiyun Zhao,Guijun Qin,Qin Wan,Gang Chen,Meng Dai,Di Zhang, Bihan Qiu, Xiaoyan Zhu,Ruixin Liu,Xiao Wang,Xulei Tang,Zhengnan Gao,Feixia Shen,Xuejiang Gu,Zuojie Luo,Yingfen Qin,Li Chen,Xinguo Hou,Yanan Huo,Qiang Li,Guixia Wang,Yinfei Zhang,Chao Liu,Youmin Wang,Shengli Wu,Tao Yang,Huacong Deng,Jiajun Zhao,Yiming Mu,Guowang Xu,Shenghan Lai,Donghui Li,Guang Ning,Weiqing Wang,Yufang Bi,Jieli Lu

Life metabolismno. 2 (2025): loaf001-loaf001

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Single-cell Transcriptome-Wide Mendelian Randomization and Colocalization Reveals Immune-Mediated Regulatory Mechanisms and Drug Targets for COVID-19

Hui Ying,Xueyan Wu, Xiaojing Jia, Qianqian Yang, Haoyu Liu, Huiling Zhao, Zhihe Chen,Min Xu,Tiange Wang,Mian Li,Zhiyun Zhao,Ruizhi Zheng, Shuangyuan Wang,Hong Lin,Yu Xu,Jieli Lu,Weiqing Wang,Guang Ning,Jie Zheng,Yufang Bi

EBioMedicine (2025): 105596-105596

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Shared Genetic Architecture of Type 2 Diabetes with Muscle Mass and Function and Frailty Reveals Comorbidity Etiology and Pleiotropic Druggable Targets

Chun Dou,Dong Liu,Lijie Kong, Mingling Chen,Chaojie Ye,Zheng Zhu,Jie Zheng,Min Xu,Yu Xu,Mian Li,Zhiyun Zhao,Jieli Lu,Yuhong Chen,Guang Ning,Weiqing Wang,Yufang Bi,Tiange Wang

METABOLISM-CLINICAL AND EXPERIMENTAL (2025)

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Effects of the Maternal and Fetal Proteome on Birth Weight: a Mendelian Randomization Analysis

Nancy McBride,Alba Fernández-Sanlés,Marwa Al Arab,Tom A Bond,Jie Zheng,Maria C Magnus,Elizabeth C Corfield,Gemma L Clayton,Liang-Dar Hwang,Robin N Beaumont,David M Evans,Rachel M Freathy,Tom R Gaunt,Deborah A Lawlor,Maria Carolina Borges

medRxiv the preprint server for health sciences（2025）

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Identifying PDAP1 As a Biological Target on Human Longevity: Integration of Mendelian Randomization, Cohort, and Cell Experiments Validation Study

Tianzhichao Hou, Zimo Sha,Qi Wang,Yuanyue Zhu,Zheng Zhu, Huajie Dai, Yijie Zhu,Tiange Wang,Mian Li, Zhiyun Zhao,Yu Xu,Jieli Lu,Jie Zheng,Jing Ye,Weiqing Wang,Guang Ning,Yufang Bi,Weiguo Hu,Min Xu

Aging cellpp.e70065-e70065, (2025)

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The Effect of Histo-Blood Group ABO System Transferase (BGAT) on Pregnancy Related Outcomes：A Mendelian Randomization Study

Yuqi Sun, Haonan Zheng, Manqing Wang, Rongrong Gu,Xueyan Wu,Qian Yang,Huiling Zhao,Yufang Bi,Jie Zheng

Computational and Structural Biotechnology Journal（2024）

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Papers共 186 篇Author StatisticsCo-AuthorSimilar Experts