He is a physician-scientist devoted to multidisciplinary clinical and epidemiological research. His long-term research interest and strategic focus are towards elucidating the contribution of 24-h blood pressure, the development and progression of neurological age-related diseases such as glaucoma diseases, cerebral small vessel diseases, cognitive decline, Alzheimer’s Disease, and cardiovascular complications. Dr. Melgarejo aims to improve the risk stratification of age-related diseases by understanding circadian rhythms and variability in blood pressure. He is interested in conducting innovative and practicable research to test hypotheses necessary to change public health actions and clinical practice, especially in underserved areas. He is transitioning his research towards understanding how social determinants of health impact the regulation of the vascular system and Alzheimer’s disease-related disorders.