Jerry Pelletier

McGill Cancer Center, McGill University, Montreal, Quebec, Canada

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Papers150 papers

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A Comparative Study of Small Molecules Targeting eIF4A

Sai Kiran Naineni, Rayelle Itoua Maiga, Regina Cencic, Andrea A Putnam, Luis A Amador, Abimael D Rodriguez,Eckhard Jankowsky,Jerry Pelletier

RNA (New York, N.Y.), (2020)

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General and Target-Specific DExD/H RNA Helicases in Eukaryotic Translation Initiation

Leo Shen,Jerry Pelletier

International Journal of Molecular Sciences, no. 12 (2020): 4402

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TACIMA-218: A NOVEL PRO-OXIDANT AGENT EXHIBITING SELECTIVE ANTI-TUMORAL ACTIVITY

Jamilah Abusarah, Yun Cui,Nehme El-Hachem, Abed El-Hakim El-Kadiry,Ian Hammond-Martel,Hugo Wurtele, Annie Beaudry,Noël J-M Raynal,Francis Robert,Jerry Pelletier, Maja Jankovic, Francois Mercier

Molecular cancer therapeutics, (2020)

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Amygdala inhibitory neurons as loci for translation in emotional memories

Prerana Shrestha, Zhe Shan,Maggie Mamcarz, Karen San Agustin Ruiz, Adam T Zerihoun, Chien-Yu Juan, Pedro M Herrero-Vidal,Jerry Pelletier,Nathaniel Heintz,Eric Klann

Nature, no. 7829 (2020): 407-411

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The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest

Mohamed Moustafa-Kamal, Thomas J Kucharski, Wissal El-Assaad,Yazan M Abbas, Valentina Gandin,Bhushan Nagar,Jerry Pelletier,Ivan Topisirovic,Jose G Teodoro

Cell reports, no. 1 (2020): 108230

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Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions

Jutta Steinberger, Leo Shen, Stephen J Kiniry, Sai Kiran Naineni,Regina Cencic, Mehdi Amiri, Sarah A E Aboushawareb,Jennifer Chu, Rayelle Itoua Maïga, Brahm J Yachnin,Francis Robert,Nahum Sonenberg

Nucleic acids research, no. 17 (2020): 9521-9537

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RNA-tethering assay and eIF4G:eIF4A obligate dimer design uncovers multiple eIF4F functional complexes

Francis Robert,Regina Cencic, Renying Cai, T Martin Schmeing,Jerry Pelletier

Nucleic acids research, no. 15 (2020): 8562-8575

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Abstract 6507: Inhibition of the translation initiation factor eIF4A1 enhances tumor cell radiosensitivity

Stacey L. Lehman, Theresa Wechsler, Kayla R. Schwartz,Amy Wahba,Lauren E. Brown,John A. Porco,Jerry Pelletier,Kevin Camphausen,Philip J. Tofilon

Cancer Research, (2020): 6507-6507

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A CRISPR-based Screen Links an Inhibitor of Nonsense-mediated Decay to eIF4A3 Target Engagement

Regina Cencic, Sai Kiran Naineni, Lauren Pugsley, Patrick Senechal, Ananya Sahni,Jerry Pelletier

ACS chemical biology, no. 6 (2020): 1621-1629

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Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference

Maryam Habibian, S Harikrishna, Johans Fakhoury, Maria Barton, Eman A Ageely,Regina Cencic, Hassan H Fakih,Adam Katolik, Mayumi Takahashi,John Rossi,Jerry Pelletier,Keith T Gagnon

Nucleic acids research, (2020)

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Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

Jennifer Chu, Wenhan Zhang,Regina Cencic,Patrick B F O'Connor,Francis Robert, William G Devine, Asher Selznick, Thomas Henkel,William C Merrick,Lauren E Brown,Pavel V Baranov,John A Porco

Cell Reports, no. 8 (2020): 2481-2488.e5

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A Meroisoprenoid, Heptenolides, and C -Benzylated Flavonoids from Sphaerocoryne gracilis ssp. gracilis

Gasper Maeda,Joan J E Munissi, Sofia Lindblad,Sandra Duffy,Jerry Pelletier,Vicky M Avery,Stephen S Nyandoro, Máté Erdélyi

Journal of natural products, no. 2 (2020): 316-322

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O-GlcNAcylation of core components of the translation initiation machinery regulates protein synthesis

Xuexia Li, Qiang Zhu, Xiaoliu Shi, Yaxian Cheng, Xueliu Li, Huan Xu,Xiaotao Duan,Linda C Hsieh-Wilson,Jennifer Chu,Jerry Pelletier, Maowei Ni, Zhiguo Zheng

Proceedings of the National Academy of Sciences of the United States of America, no. 16 (2019): 201813026

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Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors

Jennifer Chu, Wenhan Zhang,Regina Cencic, William G Devine,Dmitri Beglov, Thomas Henkel,Lauren E Brown,Sandor Vajda,John A Porco,Jerry Pelletier

Cell Chemical Biology, no. 11 (2019): 1586-1593.e3

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Correction for Dauber et al., “The Herpes Simplex Virus 1 vhs Protein Enhances Translation of Viral True Late mRNAs and Virus Production in a Cell Type-Dependent Manner”

Bianca Dauber,Jerry Pelletier,James R. Smiley

Journal of Virology, no. 17 (2019)

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Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products

Leo Shen,Jerry Pelletier

Natural product reports, (2019)

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Chemical Synthesis Enables Structural Reengineering of Aglaroxin C Leading to Inhibition Bias for Hepatitis C Viral Infection

Wenhan Zhang, Shufeng Liu,Rayelle I. Maiga,Jerry Pelletier,Lauren E. Brown, Tony T. Wang,John A. Porco

Journal of the American Chemical Society, no. 3 (2019): 1312-1323

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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

Karina Chan,Francis Robert, Christian Oertlin, Dana Kapeller-Libermann, Daina Avizonis, Johana Gutierrez, Abram Handly-Santana, Mikhail Doubrovin, Julia Park, Christina Schoepfer, Brandon Da Silva, Melissa Yao

Nature communications, no. 1 (2019): 5151-16

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A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii

Stephen S Nyandoro, Gasper Maeda, Joan J E Munissi, Amra Gruhonjic, Paul A Fitzpatrick, Sofia Lindblad,Sandra Duffy,Jerry Pelletier, Fangfang Pan, Rakesh Puttreddy,Vicky M Avery, Máté Erdélyi

Molecules (Basel, Switzerland), no. 15 (2019): 2746

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Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity

Ana Cláudia Gonçalves, Emily R Towers, Naila Haq,John A Porco,Jerry Pelletier,Sally J Dawson,Jonathan E Gale

Scientific reports, no. 1 (2019): 12501-9

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