Jerome Jatzlau

My research focuses on the BMP-mediated communication between cells. How are BMP signals differently perceived ( determination of receptor/ligand affinities), and how are these signals translated into a functional consequence (SMAD-DNA recognition and target gene regulation). To answer these questions we apply state of the art microscopy techniques and sequencing methods. We translate this question into disease relevant contexts, and ask how mechano-sensitive pathways modulate the BMP-dialogue.