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His research focuses on understanding 1) the signaling events and molecular mechanisms involved in the formation of neuronal connections during development, and 2) the molecular mechanisms underlying changes in or loss of neuronal connectivity during neurological disease (in particular amyotrophic lateral sclerosis (ALS)). This research concentrates on mouse models and humanized cell models (iPSC, organoids, microfluidics) using an integrated approach involving molecular biology, cell biology, neuroanatomy, (in vivo) functional proteomics, imaging, HC screening, and mouse genetics.
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论文共 9 篇作者统计合作学者相似作者
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2023)
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Yan Wang, Charlotte van Dijk, Ilia Timpanaro,Paul Hop,Brendan Kenna,Maarten Kooyman,Eleonora Aronica,Jeroen Pasterkamp,Leonard van den Berg,Johnathan Cooper-Knock, Project MinE ALS sequencing consortium,NYGC ALS consortium,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2022)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2021)
Current Biologyno. 21 (2020): 4328-4328
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