Chen Jeremy - Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center

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Development of AB-2100, an Autologous Integrated Circuit T (ICT) Cell Therapy Targeting CA9 Intended for the Treatment of Ccrcc

Mark Landon,Irene Scarfo,Marvin Chew, Rakesh Sudhakah,Michelle Nguyen,Suchismita Mohanty,Jeremy Chen,Alma Gomez,Nickolas Attanasio,Amanda Fearon,Ivan Chan,Vibhavari Sail,Thomas Gardner,Beatriz Millare,Vince Thomas,Stanley Zhou,Jenessa Smith,Jennifer Mcdevitt,Angela Boroughs,Levi Gray-Rupp

Journal of Clinical Oncologyno. 4_suppl (2024): 472-472

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Abstract B037: AB-2100, a PSMA-inducible CA9-specific CAR T Cell Product Intended for the Treatment of Ccrcc Provides Long-Term Tumor Responses in Preclinical Mouse Model

Suchismita Mohanty,Jeremy Chen,Alma Gomez,Angela Boroughs,Irene Scarfo,Laura Lim,Kevin Dang,Marvin Chew, Rakesh Sudhakar,Michelle Nguyen,Thomas Gardner,Beatriz Millare,James Zhang,Darrian Moskowitz,Stanley Zhou, Neroli H. Xie,Nickolas Attanasio,Amanda Fearon,Ivan Chan,Vibhavari Sail,Vince Thomas, Jennesa Smith,Jennifer McDevitt,Levi Gray-Rupp, Alba Gonzalez,Christopher Murriel,W. Nicholas Haining

Cancer Immunology Researchno. 10_Supplement (2024)

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Development of AB-2100, a PSMA-Inducible Anti-CA9 Car T Cell Therapy Intended for the Treatment of Ccrcc

Irene Scarfo,Mark Landon, Rakesh Sudhakah,Michelle Nguyen,Suchismita Mohanty,Jeremy Chen,Alma Gomez,Nickolas Attanasio,Amanda Fearon,Ivan Chan, Christine Nelson,Thomas J. Gardner,Darrian Moskowitz,Vince Thomas,Stanley Zhou,Angela Boroughs, Jennesa Smith,Jennifer McDevitt,Levi Gray-Rupp

MOLECULAR THERAPYno. 4 (2024): 404-405

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AB-2100, a PSMA-inducible CA9-specific CAR T Cell Product for the Treatment of Ccrcc Provides Long-Term Tumor Responses in Preclinical Mouse Model

Cancer Researchno. 6_Supplement (2024): 38-38

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Development of Logic-Gated "payload" Module in CAR T Cells; Aimed at Increasing Local Concentration of a Secreted ProInflammatory Molecule in an Antigen-Dependent Manner

Gavin E. Shavey, Joseph H. Choe, Audrey Fung, Luke Cassereau,Marian Sandoval, Emily Ng, Suchi Mohanty,Jeremy Chen,Alma Gomez,Sofia Kyriazopoulou Panagiotopoulou, Alba Gonzalez,Aaron Cooper,Nick Haining

MOLECULAR THERAPYno. 4 (2024): 406-406

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Synthetic Pathway Activators (SPAs) Increase Engineered T-Cell Potency and Persistence through Tunable STAT Activation

Anzhi Yao,Thomas J. Gardner,Beatriz Millare,Ashley Cass,Suchismita Mohanty,Jeremy Chen,Alma Gomez,David DeTomaso,Lionel Berthoin, Meng Lim, Azalea Ong,Vince Thomas,Nicholas Quant,Aaron R. Cooper,Levi Gray-Rupp,Angela C. Boroughs,W. Nicholas Haining

MOLECULAR THERAPYno. 4 (2023): 648-648

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301 Preclinical Development of AB-2100, a PSMA Neovasculature-Inducible CA9 CAR Resistant to FASL and TGFb Mediated Suppression for the Treatment of Ccrcc

Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)

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259 Discovery of Synthetic Signaling Pathway Receptors That Increase the Potency of CAR-T Cells Through Optimized STAT Activity

Lan Chen,Beatriz Millare,Jeremy Chen,Aaron Cooper,Natalie Bezman,Angela Boroughs,Suchismita Mohanty,David DeTomaso,Amy-Jo Casbon,Thomas J Gardner,Anzhi Yao,Ashley Cass,Alma Gomez,Manching Ku,Lionel Berthoin, Meng Lim, Azalea Ong,Vince Thomas,Nicholas Quant, Brian Hsu,Levi Gray-Rupp,W Nicholas Haining

Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)

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Multiplexed Shrna Cassettes Targeting Orthogonal Pathways (FAS/PTPN2/TGFBR) Enhance the Potency of Integrated Circuit T Cells (icts) in Multiple Solid Tumor Models

Cancer Researchno. 7_Supplement (2023): 1768-1768

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A Study of Alternative Timeframes and Descriptors for EQ-5D-5L in Obstructive Airway Diseases

Ai-Ping Chua,Bas Janssen,Jeremy Chen,Le Ann Chen,Mei Xia Liao, Nalusamy Navashar, Jan Busschback,Nan Luo

RESPIROLOGY（2023）

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