基本信息
浏览量:3
职业迁徙
个人简介
The Mottram laboratory works on the molecular genetics, cell biology and biochemistry of the parasitic protozoa that cause neglected tropical diseases such as leishmaniasis and Human African Trypanosomiasis (HAT). The primary research goal of the laboratory is to understand the molecular mechanisms by which Leishmania and Trypanosoma parasites undergo cellular remodelling during their complex life cycles. The laboratory’s focus is on cell signalling pathways that are regulated by protein kinases and the turnover of proteins and organelles that occur through the action of peptidases associated with endocytic and autophagic pathways.
The laboratory is also interested virulence factors that influence the host-parasite interaction, with a particular focus on natural peptidase inhibitors, natural variation in the Leishmania genome and new methods for monitoring disease progression. Our ultimate goal is to identify novel molecular mechanisms that can be exploited for the development of anti-parasite therapies.
研究兴趣
论文共 320 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Trends in parasitologyno. 3 (2024): 211-213
Molecular and Biochemical Parasitology (2024): 111619-111619
EMBO Reportsno. 3 (2024): 1075-1105
Catherine N. Russell, Jennifer L. Carter, Juliet M. Borgia,Jacob Bush,Felix Calderon,Raquel Gabarro,Stuart J. Conway,Jeremy C. Mottram,Anthony J. Wilkinson,Nathaniel G. Jones
ACS INFECTIOUS DISEASESno. 11 (2023): 2340-2357
SCIENCEno. 6652 (2023): 1349-1356
Autophagy reportsno. 1 (2023)
The Journal of eukaryotic microbiologyno. 6 (2023): e12994-e12994
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn