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We seek to understand how the nervous system learns and makes decisions in dynamic environments. We are currently studying how neurons that release monoamines (serotonin, norepinephrine, and dopamine) are involved in decision making. These neurons make up less than one-thousandth of one percent of the neurons in our brain, yet they broadcast their signals to most of the brain. Many disorders, including depression, schizophrenia, drug addiction, and Parkinson's disease, appear to involve dysfunction of monoaminergic signaling. Using cell-type-specific neurophysiology, theory, computation, and well-controlled behavioral tasks in mice, we aim to understand the functions of monoaminergic neurons and their targets in cortex and basal ganglia. We hope these basic discoveries will lead to an understanding of the biology of the nervous system and better treatments for its disorders.
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Eric A. Finkel,Yi-Ting Chang, Rajan Dasgupta, Emily E. Lubin,Duo Xu,Genki Minamisawa,Anna J. Chang,Jeremiah Y. Cohen,Daniel H. O’Connor
Cell Reportsno. 4 (2024): 113991-113991
Fuat Balci,Suliann Ben Hamed,Thomas Boraud,Sébastien Bouret,Thomas Brochier,Cédric Brun,Jeremiah Y. Cohen,Etienne Coutureau,Marc Deffains, Valérie Doyère,Georgia G. Gregoriou, J. Alexander Heimel,
Neuronno. 5 (2023): 604-605
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