Jeff Settleman

基本信息

Career Trajectory

Bio

Dr. Settleman held numerous notable positions in both academic research and drug discovery before joining the Pfizer team. Prior to his current role, Dr. Settleman served as Distinguished Principal Investigator and Head of Oncology Research at Calico Life Sciences. Prior to Calico, Dr. Settleman led Discovery Oncology at Genentech.

Research Interests

Papers共 362 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Amplification of MET May Identify a Subset of Cancers with Extreme Sensitivity to the Selective Tyrosine Kinase Inhibitor PHA- 665752 (vol 103, Pg 2316, 2006)

Gromoslaw A. Smolen,Raffaella Sordella,Beth Muir,Gayatry Mohapatra,Anne Barmettler,Heidi Archibald,Woo J. Kim,Ross A. Okimoto,Daphne W. Bell,Dennis C. Sgroi,James G. Christensen,Jeffrey Settleman,Daniel A. Haber

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA（2024）

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Supplementary Figure 7 from Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M

Ho-June Lee,Gabriele Schaefer,Timothy P. Heffron,Lily Shao,Xiaofen Ye,Steve Sideris,Shiva Malek,Emily Chan,Mark Merchant,Hank La,Savita Ubhayakar,Robert L. Yauch,Valentina Pirazzoli,Katerina Politi,Jeff Settleman

openalex（2023）

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Supplementary Figures 1-11 with Legends from EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells Sustaining DNA Double-Strand Breaks

Meng Wang,Fabian Morsbach,David Sander,Liliana Gheorghiu,Akash Nanda,Cyril Benes,Malte Kriegs,Mechthild Krause,Ekkehard Dikomey,Michael Baumann,Jochen Dahm-Daphi,Jeffrey Settleman,Henning Willers

openalex（2023）

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Supplementary Figure Legends from EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells Against Ionizing Radiation

Meng Wang,Ashley M. Kern,Marieke Hülskötter,Patricia Greninger,Anurag Singh,Yunfeng Pan,Dipanjan Chowdhury,Mechthild Krause,Michael Baumann,Cyril H. Benes,Jason A. Efstathiou,Jeff Settleman,Henning Willers

openalex（2023）

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Supplementary Table 2 from Activation of PI3K Signaling in Merkel Cell Carcinoma

Valentina Nardi,Youngchul Song,Juan A. Santamaria-Barria,Arjola K. Cosper,Quynh Lam,Anthony C. Faber, Genevieve M. Boland, Beow Y. Yeap,Kristin Bergethon,Vanessa L. Scialabba,Hensin Tsao,Jeffrey Settleman,David P. Ryan,Darrell R. Borger,Atul K. Bhan,Mai P. Hoang,Anthony J. Iafrate,James C. Cusack,Jeffrey A. Engelman,Dora Dias-Santagata

openalex（2023）

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Supplementary Figures 2-5 from Breast Tumor Kinase Phosphorylates P190rhogap to Regulate Rho and Ras and Promote Breast Carcinoma Growth, Migration, and Invasion

Che-Hung Shen,Hsin-Yi Chen,Ming-Shien Lin,Fang-Yen Li,Cheng-Chi Chang,Min-Liang Kuo,Jeffrey Settleman,Ruey-Hwa Chen

crossref（2023）

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Supplementary Information from Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma

Nisebita Sahu,Emily Chan,Felix Chu,Thinh Pham,Hartmut Koeppen,William Forrest,Mark Merchant,Jeff Settleman

openalex（2023）

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Supplementary Figure Legends 1-3, Table 1 from Elevated CRAF As a Potential Mechanism of Acquired Resistance to BRAF Inhibition in Melanoma

Clara Montagut,Sreenath V. Sharma,Toshi Shioda,Ultan McDermott,Matthew Ulman,Lindsey E. Ulkus,Dora Dias-Santagata,Hannah Stubbs,Diana Y. Lee,Anurag Singh,Lisa Drew,Daniel A. Haber,Jeffrey Settleman

crossref（2023）

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Suppl. Fig. 1-6 from Adapting a Drug Screening Platform to Discover Associations of Molecular Targeted Radiosensitizers with Genomic Biomarkers

Qi Liu,Meng Wang,Ashley M. Kern,Saman Khaled,Jing Han, Beow Y. Yeap, Theodore S. Hong,Jeff Settleman, Cyril H. Benes,Kathryn D. Held, Jason A. Efstathiou,Henning Willers

openalex（2023）

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Papers共 362 篇Author StatisticsCo-AuthorSimilar Experts