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To do this, they develop new technologies that integrate molecular biology, microscopy, and large-scale bioinformatics. These efforts include new methods for single-cell ATAC-seq, an increasingly popular method to measure the epigenomes of single-cells. Altogether, we broadly apply these tools to study dynamic cellular systems, including the epigenetic mechanisms underlying cell fate decisions in hematopoiesis and leukemia development.
ATAC-seq was first developed by Buenrostro and colleagues in 2013 and its use is now ubiquitous in genomics — for example in major efforts like the Human Cell Atlas project to understand and map genome function. As a reflection of the impact of this work, MIT’s Technology Review named Buenrostro as one of its 2019 “Innovators under 35”.
ATAC-seq was first developed by Buenrostro and colleagues in 2013 and its use is now ubiquitous in genomics — for example in major efforts like the Human Cell Atlas project to understand and map genome function. As a reflection of the impact of this work, MIT’s Technology Review named Buenrostro as one of its 2019 “Innovators under 35”.
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论文共 110 篇作者统计合作学者相似作者
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Tristan Tay,Gayathri Bommakanti, Elizabeth Jaensch, Aparna Gorthi, Iswarya Reddy,Yan Hu,Ruochi Zhang,Aatman Doshi, Sin Lih Tan, Verena Brucklacher-Waldert,Laura Prickett,James Kurasawa,
biorxiv(2024)
Patricia Borck, Kirsty Wienand,Fabiana Duarte, Alvin Qin,Ruochi Zhang, Juliana Babu, Simone Zhang, Samuel Maffa, Max Horlbeck, Rojesh Shrestha,Joshua Dempster,Jennifer Roth,
Cancer Researchno. 7_Supplement (2024)
Sarah M. Mangiameli,Haiqi Chen,Andrew S. Earl, Julie A. Dobkin,Daniel Lesman,Jason D. Buenrostro,Fei Chen
biorxiv(2023)
Giulia Schiroli,Vinay K Kartha,Fabiana M Duarte, Trine Ahn Kristiansen, Christina Mayerhofer,Rojesh Shrestha,Andrew Earl,Yan Hu,Tristan Tay,Catherine Rhee,Jason Buenrostro,David T Scadden
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Jingyi Wu,Luis Nicolas Gonzalez Castro,Tyler E. Miller,Sofia Battaglia, Joshua D’Antonio,Chadi A. El Farran, Margaret A. Thompson,Jason D. Buenrostro,Mario L. Suvà, B Bernstein
Neuro-oncologyno. Supplement_5 (2023): v132-v132
Florian V. De Rop,Gert Hulselmans, Chris Flerin,Paula Soler-Vila, Albert Rafels,Valerie Christiaens,Carmen Bravo González-Blas,Domenica Marchese,Ginevra Caratù,Suresh Poovathingal,Orit Rozenblatt-Rosen, Michael Slyper,
Molly M Moore, Siddarth Wekhande,Robbyn Issner, Alejandro Collins, Yanjing Liu,Nauman Javed,Jason D Buenrostro,Charles B. Epstein, Eugenio Mattei,John G Doench,Bradley E Bernstein,Noam Shoresh,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Yan Hu,Sai Ma,Vinay K Kartha,Fabiana M Duarte,Max Horlbeck,Ruochi Zhang,Rojesh Shrestha,Ajay Labade, Heidi Kletzien, Alia Meliki, Andrew Castillo,Neva Durand,
bioRxiv : the preprint server for biology (2023)
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