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A fundamental biological process is the conversion of genetic information into functional proteins. Linear protein molecules must fold into sophisticated three-dimensional structures, and interact with the appropriate cellular targets. In cells, the folding and maturation of proteins depend on a specialized class of proteins termed 'molecular chaperones'. The chaperones are critical for the prevention of protein misfolding and aggregation, which are thought to underlie several neurodegenerative disorders such as Parkinson's disease.
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Juliana C Franco,Maria L C Nogueira, Gabriela M Gandelini,Glaucia M S Pinheiro,Conrado C Gonçalves,Leandro R S Barbosa,Jason C Young,Carlos H I Ramos
Juliana C. Franco,Maria L. C. Nogueira, Gabriela M. Gandelini,Glaucia M. S. Pinheiro,Conrado C. Gonçalves,Leandro R. S. Barbosa,Jason C. Young,Carlos H. I. Ramos
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Nature Communicationsno. 1 (2023): 1-26
Afrooz Dabbaghizadeh, Alexandre Paré, Zacharie Cheng-Boivin,Robin Dagher,Sandra Minotti,Marie-Josée Dicaire,Bernard Brais,Jason C Young,Heather D Durham,Benoit J Gentil
Nathalie Bedard,Erin Coyne,Julie Huynh,Xavier Jacq, Ewelina Rozycka,Lenka Schorova,Jason Young,Simon Wing
Journal of the Endocrine Societyno. Supplement_1 (2022): A726-A726
Afrooz Dabbaghizadeh, Alexandre Paré, Zacharie Cheng-Boivin, Robin Dagher,Sandra Minotti,Marie-Josée Dicaire,Brais Bernard,Jason C. Young,Heather D. Durham,Benoit J. Gentil
bioRxiv (2021)
The American journal of pathologyno. 3 (2020): 554-562
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