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个人简介
My research vision is to apply basic biochemistry to solve medical and biological problems, and in the long run to develop new treatments of human diseases. We have designed a fully synthetic lung surfactant preparation for treatment of respiratory distress syndrome in premature infants and together with a pharmaceutical company taken it to phase II clinical development. We have also pioneered studies of a molecular chaperone, and recently shown that it has potent activity in Alzheimer disease mouse models, findings that we hope to take to human studies in the coming years. Finally, we have discovered how spider silk proteins assemble into fibers, and from this we have produced recombinant biological drugs as well as spun artificial silk. Much of this research has been performed in close, long-standing and fruitful collaborations with groups at KI as well as other universities and companies.
研究兴趣
论文共 426 篇作者统计合作学者相似作者
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EMBO molecular medicineno. 4 (2024): 715-716
Journal of pharmaceutical and biomedical analysis (2023): 115465-115465
Clinical & experimental optometrypp.1-8, (2023)
Tina Arndt,Urmimala Chatterjee,Olga Shilkova,Juanita Francis, Johan Lundkvist, Daniel Johansson,Benjamin Schmuck,Gabriele Greco,Asa Ekblad Nordberg,Yan Li, Lars U. Wahlberg,Maud Langton,
ADVANCED FUNCTIONAL MATERIALS (2023)
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RSC MEDICINAL CHEMISTRYno. 5 (2023): 848-857
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Protein Scienceno. 6 (2023)
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Xingmei Qi,Yu Wang,Hairui Yu, Ruifang Liu,Axel Leppert, Zihan Zheng,Xueying Zhong,Zhen Jin, Han Wang,Xiaoli Li,Xiuzhe Wang,Michael Landreh,
Small (Weinheim an der Bergstrasse, Germany)no. 46 (2023)
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Laurène Adam,Rakesh Kumar,Luis Enrique Arroyo-Garcia, Willem Hendrik Molenkamp,Jan Stanislaw Nowak, Hannah Klute,Azad Farzadfard, Rami Alkenayeh,Janni Nielsen,Henrik Biverstål,Daniel E. Otzen,Jan Johansson,
biorxiv(2023)
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