基本信息
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职业迁徙
个人简介
PhD Cell Biology and Physiology, University of Alberta。 Post-Doctoral Fellowship, Washington University Medical Center。
Major Awards:
2014 Killam Research Fellowship。
2009 Researcher of the Year – Department of Cellular and Physiological Sciences。
2008 UBC Faculty of Medicine Distinguished Achievement Award for Excellence in Basic Science Research。
2007 Murray L Barr Award, Canadian Association for Anatomy Neurobiology and Cell Biology。
2006 Canadian Diabetes Association Scholarship (declined)。
2006 Canadian Institute of Health Research New Principal Investigator Award。
2005 Juvenile Diabetes Research Foundation Career Development Award。
publication:
Johnson JD†, Bernal-Mizrachi E, Alejandro E, Han Z, Kalynyak T, Li H, Beith JL, Gross J, Warnock GL, Townsend RR, Permutt MA, Polonsky KS. 2006. Insulin protects islets from apoptosis via pdx-1 and specific changes in the human islet proteome. Proc. Natl. Acad. Sci. USA. (Track II).103: 19575-80.
•• Provides evidence for anti-apoptotic effects of insulin on mouse and human beta-cells. 1st proteomic analysis of the human islet proteome under 2 conditions.Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, Marsh BJ, Johnson JD, Parks JS, Verchere CB, Hayden MR. 2007. -Cell ABCA1 Influences Insulin Secretion, Glucose Homeostasis and Response to Thiazolidinedione Treatment. Nature Medicine. 13: 230-7.
•• 1st study on the role of any cholesterol transporter in beta-cells.Dror V, Nguyen V, Walia P, Kalynyak TB, Hill JA, Johnson JD†. 2007. Notch signalling suppresses apoptosis in adult pancreatic islet cells. Diabetologia 50:2504-15.
•• 1st study of Notch signalling in adult islets. 1st demonstration that Neurogenin 3 protein is present and can be modulated in adult islets (the presence of Neurogenin 3 was controversial at the time but has since been vindicated).Beith JL, Alejandro EU, Johnson JD†. 2008. Insulin stimulates primary β-cell proliferation via raf-1 kinase. Endocrinology. 149:2251-60.
研究兴趣
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Nature Protocolspp.1-31, (2024)
Tobias Boothe,Gareth E Lim, Haoning Cen,Søs Skovsø,Micah Piske, Shu Nan Li, Ivan R Nabi,Patrick Gilon,James D Johnson
Molecular metabolismpp.101935-101935, (2024)
Risha Banerjee, Ying Zhu,George P Brownrigg, Renata Moravcova,Jason C Rogalski,Leonard Foster,James D Johnson,Jelena Kolic
biorxiv(2024)
Jelena Kolic,WenQing Grace Sun,Haoning Howard Cen,Jessica Ewald,Jason C Rogalski,Shugo Sasaki,Han Sun, Varsha Rajesh,Yi Han Xia, Renata Moravcova,Søs Skovsø,Aliya F Spigelman,
medRxiv : the preprint server for health sciences (2024)
Anni M. Y. Zhang,Yi Han Xia, Jeffrey S. H. Lin,Ken H. Chu,Wei Chuan K. Wang, Titine J. J. Ruiter,Jenny C. C. Yang,Nan Chen,Justin Chhuor,Shilpa Patil, Haoning H. Cen,Elizabeth J. Rideout,
CANCER RESEARCHno. 2 (2024)
Tobias Boothe,Gareth E. Lim, Haoning Cen,Søs Skovsø,Micah Piske, Shu Nan Li, Ivan R. Nabi,Patrick Gilon,James D. Johnson
Molecular Metabolism (2024): 101935
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AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISMno. 1 (2024): E61-E72
Tobias Boothe,Gareth E. Lim, Haoning Cen,Søs Skovsø,Micah Piske, Shu Nan Li, Ivan R. Nabi,Patrick Gilon,James D. Johnson
DIABETOLOGIAno. SUPPL 1 (2023): S222-S222
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Journal of the Society for Cardiovascular Angiography & Interventionsno. 3 (2023): 100692-100692
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