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Dr. Xiang’s lab is interested in studying cellular and molecular mechanisms for CD4 T cell help in CD8 cytotoxic T lymphocyte (CTL) responses and memory and developing novel exosome-targeted T cell-based immunotherapeutic vaccines for HER2-positive breast cancer and HIV-1 patients. Recently, Dr. Xiang’s group discovered the critical role of mannose-6-phosphate Receptor (M6PR) in regulation of T cell fate. Currently, his team is elucidating the molecular pathways for pro-survival cytokine-induced differential M6PR expression-regulated CTL contraction and memory.
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论文共 270 篇作者统计合作学者相似作者
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Michelle Yu,Jim Xiang
Clinical Research in Oncologyno. 1 (2024): 6-9
CELLULAR & MOLECULAR IMMUNOLOGYno. 3 (2023): 311-312
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International Journal of Molecular Sciencesno. 17 (2022): 9534
The Journal of Immunologyno. 1_Supplement (2022): 55.08-55.08
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