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职业迁徙
个人简介
The research of my group focusses on the evolution of bacterial pathogens; their origin, transmission and adaptation to selective pressure. I primarily use genomic and phylogenetic approaches to address these, and over the last few years my group has used large-scale population genomics to identify the global origin and routes of spread of many human and animal pathogens. Overlaid on the phylogeny, we look for signatures of adaptation to the host, to antibiotics and to vaccine pressure, most recently developing bacterial genome-wide association approaches to identify genetic determinants responsible for this adaptation. In addition to informatics approaches, we develop and apply genome-wide experimental tools, studying interaction with the host and antimicrobial resistance mechanisms. We have an interest in metagenomics, currently studying the microbiota in the gut, the lung, the nasopharynx and the placenta (which doesn’t have one). We often work at an international level, with many collaborations in Low- and Middle-Income countries.
研究兴趣
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The Lancet. Microbeno. 2 (2024): e151-e163
Beth Blane,Kathy E Raven, Nicholas M Brown,Ewan M Harrison,Francesc Coll,Rachel Thaxter,David A Enoch,Theodore Gouliouris,Danielle Leek, Sophia T Girgis, Asha Akram,Marta Matuszewska,
Microbial genomicsno. 4 (2024)
The Lancet. Microbeno. 2 (2024): e142-e150
Kavita De,Juan M Belardinelli,Arun Prasad Pandurangan, Teddy Ehianeta,Elena Lian,Zuzana Palčeková, Ha Lam,Mercedes Gonzalez-Juarrero,Josephine M Bryant,Tom L Blundell,Julian Parkhill, R Andres Floto,
Proceedings of the National Academy of Sciences of the United States of Americano. 17 (2024): e2403206121-e2403206121
GUT (2024)
Liping Li,Francesca L. Short,Karl A. Hassan,Varsha Naidu,Alaska Pokhrel,Stephanie S. Nagy, Farzana T. Prity,Bhumika S. Shah, Nusrat Afrin,Stephen Baker,Julian Parkhill,Amy K. Cain,
Nature Microbiologyno. 11 (2023): 1-11
Frontiers in microbiology (2023): 1185753
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