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I worked on the biochemistry of pancreatic bicarbonate secretion. I decided to switch from biochemistry to physiology because I had developed an interest in the mechanisms underlying high blood pressure. Hence, I came to the Department of Physiology at the University of Maryland to work on that problem. My work led to the discovery of endogenous ouabain. In the years that followed, I was fortunate to be involved with work going from molecules through to clinical studies. My lab is now focused primarily on ouabain, aldosterone and opiates in the brain.
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American journal of physiology. Cell physiology (2024)
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