Dr. Frenje’s research is conducted in the areas of High-Energy-Density-Plasmas (HEDP), Inertial Confinement Fusion (ICF), and nuclear physics. Together with his students, a wide range of diagnostics are built and used to support of the ICF programs at the OMEGA laser facility at Laboratory for Laser Energetics at the University of Rochester, the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory, and the Z facility at Sandia National Laboratory, as well as to conduct basic-science experiments at these facilities. In addition, Dr. Frenje has pioneered a new field of research, called plasma nuclear science, which blends the disciplines of plasma and nuclear physics. In his pioneering experiment, he demonstrated for the first time that an ICF facility and HEDP can be used to study basic nuclear physics.