Isabelle Krimm

At the Center for Cancer Research in Lyon, our team "Small Molecules For Biological Targets" develops small bioactive molecules with two objectives: - the design of small-molecule tools to explore biological pathways involved in cancer (chemical probes) - the design of therapeutic compounds to fight cancer (drug-candidate). We use fragment-based techniques and structure-based design approaches to develop VDAC chemical probes and novel CK2 inhibitors.