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职业迁徙
个人简介
My group are investigating the control of meiotic recombination frequency in plant genomes by genetic and epigenetic factors. For example, we have worked extensively to show that crossover frequency is shaped by euchromatin and heterochromatin at the scale of hotspots and whole chromosomes. Using natural genetic variation we have identified the first recombination modifier loci that shape crossover frequency in different parts of the genome. We predominantly use the model plant Arabidopsis thaliana for our studies, but we are also seeking to translate this knowledge into agricultural species, for example wheat and tomato, in order to accelerate breeding as we adapt our crops to the changing climate. Most recently we have been using long read DNA sequencing, including nanopore, to assemble highly repetitive regions of plant genomes, for example the centromeres. We are interested to explore how chromatin and recombination pathways interact to control the repeat architecture of these regions.
研究兴趣
论文共 157 篇作者统计合作学者相似作者
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Joiselle B. Fernandes,Matthew Naish,Qichao Lian,Robin Burns,Andrew J. Tock,Fernando A. Rabanal,Piotr Wlodzimierz, Anette Habring, Robert E. Nicholas,Detlef Weigel,Raphael Mercier,Ian R. Henderson
Genome Biologyno. 1 (2024): 1-31
Heejin Kim,Jaeil Kim,Namil Son,Pallas Kuo, Chris Morgan,Aurélie Chambon,Dohwan Byun,Jihye Park, Youngkyung Lee,Yeong Mi Park, John A. Fozard, Julie Guérin,
Nature Plantsno. 3 (2024): 453-468
Genome researchno. 2 (2024): 161-178
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Piotr Wlodzimierz,Fernando A. Rabanal,Robin Burns,Matthew Naish,Elias Primetis,Alison Scott,Terezie Mandáková, Nicola Gorringe,Andrew J. Tock,Daniel Holland,Katrin Fritschi, Anette Habring,
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Nature communicationsno. 1 (2023): 6716-16
bioRxiv : the preprint server for biology (2023)
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Nature plantsno. 3 (2023): 379-380
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