基本信息
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个人简介
Immune tolerance:
Long-standing and present focus on CD8+ Tregs and mediators of tolerance by these cells, such as IL-34. Implementation of methods for cell therapy with CD8+ Tregs.
Presently developing strategies to increase endogenous sources of Tregs through the use of anti-CD45RC MAbs depleting CD45RChigh Teff cells and sparing CD8+ and CD4+ CD45RClow Tregs.
Gene editing and gene transfer techniques:
Long lasting and present focus in the generation of genetically modified rats using ZFNs, TALENs and CRISPRs.
The use of viral gene transfer vectors for immune mediators.
Long-standing and present focus on CD8+ Tregs and mediators of tolerance by these cells, such as IL-34. Implementation of methods for cell therapy with CD8+ Tregs.
Presently developing strategies to increase endogenous sources of Tregs through the use of anti-CD45RC MAbs depleting CD45RChigh Teff cells and sparing CD8+ and CD4+ CD45RClow Tregs.
Gene editing and gene transfer techniques:
Long lasting and present focus in the generation of genetically modified rats using ZFNs, TALENs and CRISPRs.
The use of viral gene transfer vectors for immune mediators.
研究兴趣
论文共 454 篇作者统计合作学者相似作者
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Stem Cell Research & Therapyno. 1 (2024): 1-18
medRxiv (Cold Spring Harbor Laboratory) (2023)
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BMC Biologyno. 1 (2023)
Sandra Martin Lorenzo,Maria Del Mar Muniz Moreno, Helin Atas, Marion Pellen,Valérie Nalesso, Wolfgang Raffelsberger, Geraldine Prevost,Loic Lindner,Marie-Christine Birling,Séverine Menoret,Laurent Tesson,Luc Negroni,
biorxiv(2023)
Molecular therapy. Methods & clinical development (2023): 30-47
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iScienceno. 4 (2023): 106399-106399
Gwladys Gernoux,Mickael Guilbaud,Marie Devaux,Nicolas Jaulin,Virginie Pichard, Allan Avenel, Anthony Mellet,Johanne Le Duff, Rebecca Xicluna,Apolline Salama,Carole Guillonneau,Ignacio Anegon,
MOLECULAR THERAPYno. 4 (2023): 657-658
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