基本信息
浏览量:16
职业迁徙
个人简介
Mitochondria are vitally important organelles within living cells and are often described as their powerhouses. They generate the primary energy for all biological activities, from ATP generation to cell growth and death (apoptosis). It is no surprise, therefore, mitochondrial dysfunction leads to life threatening diseases, such as cancer, diabetes, stroke, and various neurodegenerative diseases (e.g. Alzheimer’s and Parkinson’s diseases). Structurally, mitochondria have two membranes dividing the organelle into four sub-compartments: outer membrane (OM), intermembrane space (IMS), inner membrane (IM), and matrix. Mitochondria contain about 1500 proteins and ~99% of the proteins are synthesized in the cytosol and post-transnationally imported into the organelle for function. Research in my group focuses on (1) understanding the molecular mechanisms of mitochondrial protein quality control; (2) understanding the mechanisms of key proteins involved in mitochondrial protein import and folding, and their application in enhance oxidative folding of industrial important proteins; as well as (3) exploring graphene assembly and its application in biology.
研究兴趣
论文共 44 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn