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个人简介
His current work centers on further improvement of liposome and naked DNA vectors for gene transfer in tumor and lung, and the use of ligand targeted plasmid and synthetic DNA for gene transfer in the liver. These technologies are being tested in animal models for gene therapy of cancer, wound healing and pulmonary disorders. He is also developing intravesical drug delivery system for treating hypersensitive bladder. One of the vectors developed in his lab, LPD nanoparticles, can also be used to deliver peptide and protein antigens to the dendritic cells to stimulate both protective and therapeutic immune responses against HPV+ cervical cancer in a mouse model. Dr. Huang's research has been supported by NIH and other agencies for the last 28 years. He has authored or co-authored more than 260 peer-reviewed papers and more than 90 reviews and book chapters. He is also the inventor or co-inventor for 13 US and foreign patents. Dr. Huang is active in several professional societies. He was the chairman of the non-viral gene therapy committee of the American Society of Gene Therapy and has organized several workshops for the Controlled Release Society and a biannual meeting of the Liposome Research Days. Dr. Huang also co-founded two biotech start-up companies.
研究兴趣
论文共 514 篇作者统计合作学者相似作者
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JOURNAL OF CONTROLLED RELEASE (2024): 500-514
Lei Miao,Qi Liu, C. Michael Lin,Cong Luo,Yuhua Wang,Lina Liu,Weiyan Yin,Shihao Hu,William Y. Kim,Leaf Huang
crossref(2023)
Hossein Sendi,Mostafa Yazdimamaghani,Mengying Hu, Nikhila Sultanpuram, Jie Wang, Amber S. Moody, Ellie McCabe, Jiajie Zhang, Amanda Graboski,Liantao Li,Juan D. Rojas,Paul A. Dayton,
crossref(2023)
Menglin Wang,Benoit Rousseau,Kunyu Qiu, Guannan Huang,Yu Zhang, Hang Su,Christine Le Bihan-Benjamin,Ines Khati, Oliver Artz,Michael B Foote,Yung-Yi Cheng,Kuo-Hsiung Lee,
Nature biotechnologypp.1-12, (2023)
Xiaoyu Liu,Jingying Zhou,Haoran Wu, Shufen Chen,Lingyun Zhang,Wenshu Tang,Liang Duan,Ying Wang, Eleanor McCabe,Mengying Hu,Zhuo Yu,Hanzhuang Liu,
Molecular therapy : the journal of the American Society of Gene Therapyno. 1 (2022): 119-133
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