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Research efforts in the Lashuels laboratory focus on understanding the molecular mechanisms of neurodegeneration and developing novel strategies to diagnose and treat neurodegenerative diseases such as Alzheimers and Parkinsons disease. Research in the Lashuel lab is funded by several international funding agencies and foundations, including the Swiss National Science Foundation, European FP7 program (Marie Curie and ERC grants), Human Science Frontiers, Strauss Foundation, Cure the Huntingtons disease foundation and Michael J Fox foundation and is supported by collaborations with pharmaceutical and biotech companies (http://lashuel-lab.epfl.ch/page-50538-en.html), Nestle, Merck-Serono, AC Immune and Johnson and Johnson. Dr. Lashuels research has resulted in the characterization of novel quaternary structure intermediates on the amyloid pathway, identification of potential therapeutic targets, and new hypotheses concerning the mechanisms of pathogenesis in Alzheimers disease, Parkinsons disease and related disorders. Dr. Lashuel scientific contribution to this field includes i) more than100 publications in major peer reviewed journals including Nature journals, Cell, PNAS, JBC, J. Neuroscience JACS, and Angewandtie Chemie; ii) three patents on novel strategies for preventing protein aggregation and treating autoimmune and inflammatory diseases; iii) more than 150 invited lectures since 2002 and more than 5500 citations (7800 citation-Google Scholar) since 1996. Dr. Lashuel has received several pre-doctoral and post-doctoral awards and fellowships and was the recipient of two prestigious awards given to young investigators; Human Science Frontiers young investigator research award and the European Research Council (ERC) starting independent researcher grant and the ERC proof of concept award (2013) These awards provide more than $2.5 Million to Dr. Lashuel to translate some of his ideas and projects into novel strategies for diagnosing and treating neurodegenerative diseases such as Alzheimers and Parkinsons disease. Dr. Lashuel has chaired and co-organized several international conferences and serves as an academic editor for PLoS ONE, an associate editor for frontiers of molecular neuroscience, member of the Editorial advisory board of ChemBioChem and ad hoc reviewer for several international scientific journals and funding agencies.
Research Interests
Papers共 268 篇Author StatisticsCo-AuthorSimilar Experts
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Molly E V Swanson,Adelie Y S Tan,Lynette J Tippett,Clinton P Turner,Maurice A Curtis,Emma L Scotter,Hilal A Lashuel, Mike Dragunow, Richard L M Faull,Helen C Murray, Malvindar K Singh-Bains
Scientific reportsno. 1 (2025): 15546-15546
Simon Hornung, Dominik P. Vogl,Denise Naltsas,Beatrice Dalla Volta,Markus Ballmann, Beatrice Marcon,Muhammed Muazzam Kamil Syed, Yiyang Wu,Anna Spanopoulou,Regina Feederle, Luzia Heidrich,Juergen Bernhagen,Thomas Koeglsperger, Guenter U. Hoeglinger,Gerhard Rammes,Hilal A. Lashuel,Aphrodite Kapurniotu
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2025)
ACS Chemical Neuroscienceno. 1 (2024): 193-204
ACS CHEMICAL NEUROSCIENCEno. 12 (2024): 2408-2419
Arpine Sokratian,Ye Zhou,Meltem Tatli,Kevin J. Burbidge,Enquan Xu,Elizabeth Viverette,Sonia Donzelli,Addison M. Duda, Yuan,Huizhong Li,Samuel Strader, Nirali Patel, Lauren Shiell, Tuyana Malankhanova, Olivia Chen,Joseph R. Mazzulli,Lalith Perera,Henning Stahlberg,Mario Borgnia,Alberto Bartesaghi,Hilal A. Lashuel,Andrew B. West
Science advancesno. 44 (2024): eadq3539-eadq3539
Movement disorders official journal of the Movement Disorder Societyno. 10 (2024): 1663-1678
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI (2024)
ANGEWANDTE CHEMIE-INTERNATIONAL EDITIONno. 3 (2024)
NATURE CHEMICAL BIOLOGYno. 4 (2024)
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Author Statistics
#Papers: 268
#Citation: 24121
H-Index: 82
G-Index: 152
Sociability: 7
Diversity: 4
Activity: 96
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