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个人简介
Dr. Paulson's research and clinical interests concern the causes and treatment of age-related neurodegenerative diseases, with an emphasis on polyglutamine diseases, Alzheimer's disease and frontotemporal dementia. In 1997, his lab described abnormal protein aggregates in the polyglutamine diseases, which now are recognized as a pathological hallmark in this class of inherited diseases. Using test tube, cell-based and animal models, he has contributed to advances in the understanding of various neurodegenerative diseases. His lab also helped pioneer the use of gene silencing methods as potential therapy for the many neurological disorders caused by "toxic" mutant genes.
研究兴趣
论文共 372 篇作者统计合作学者相似作者
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Rowan Saloner,Adam Staffaroni,Eric Dammer,Erik C B Johnson,Emily Paolillo, Amy Wise,Hilary Heuer,Leah Forsberg,Argentina Lario Lago, Julia Webb,Jacob Vogel, Alexander Santillo,
Research square (2024)
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETYno. 2 (2024): 183-193
Ruo-Yah Lai, Christian Rummey, Christian J. Amlang,Chi-Ying R. Lin,Tiffany X. Chen,Susan Perlman,George Wilmot, Christopher M. Gomez,Jeremy D. Schmahmann,Henry Paulson,Sarah H. Ying,Chiadi U. Onyike,
The Cerebellumpp.1-15, (2024)
Melissa J Armstrong, Yunfeng Dai, Kaitlin Sovich, Brian LaBarre,Henry L Paulson,Susan M Maixner,Julie A Fields,Angela M Lunde,Leah K Forsberg,Bradley F Boeve,Carol A Manning,James E Galvin,
Annual review of medicine (2024): 99-111
Levi Peppel,Ruo-Yah Lai,Puneet Opal,Jeremy Schmahmann,Christopher Gomez,Henry Paulson,Theresa Zesiewicz,Susan Perlman,George Wilmot, Sarah Ying,Chiadi Onyike, K Bushara,
Neurologyno. 17_supplement_1 (2024)
Melissa J Armstrong, Brian LaBarre, Kaitlin Sovich,Susan M Maixner,Henry L Paulson,Carol Manning,Julie A Fields,Angela Lunde,Leah Forsberg,Bradley F Boeve,James E Galvin,Angela S Taylor,
Alzheimer's & dementia : the journal of the Alzheimer's Associationno. 4 (2024): 2719-2730
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