基本信息
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职业迁徙
个人简介
Research interests
The main focus of my lab is mitochondria in neurodegenerative diseases, primarily focused on Parkinson’s Disease. This encompasses mitochondrial function, DNA, morphology and recycling as well as links with other cellular pathways.
My research focuses on both trying to further the understanding of the causes of mitochondrial problems in neurodegenerative conditions and in vitro drug screening for molecules which rescue mitochondrial function in patient tissue.
The lab has also recently become interested in investigating these mitochondrial abnormalities in Alzheimer’s Disease and Motor Neuron Disease patient derived cells. It is interesting to investigate the differing mitochondrial phenotypes between neurodegenerative diseases and the mechanisms by which they occur and potentially drive neuronal vulnerability.
研究兴趣
论文共 99 篇作者统计合作学者相似作者
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Calum Harvey, Marcel Weinreich, James A. K. Lee,Allan C. Shaw,Laura Ferraiuolo,Heather Mortiboys,Sai Zhang,Paul J. Hop,Ramona A. J. Zwamborn,Kristel van Eijk,Thomas H. Julian,Tobias Moll,
HELIYONno. 3 (2024): e24975-e24975
Samir Morsli,Catarina M. Henriques,Pamela S. Ellis,Heather Mortiboys, Sarah Baxendale,Catherine A. Loynes, Stephen A. Renshaw,Ilaria Bellantuono
AGING CELLno. 3 (2024)
The Biochemical journalno. 4 (2024): 265-278
Thomas Payne, Toby Burgess,Stephen Bradley, Sarah Roscoe,Matilde Sassani,Mark J. Dunning,Dena Hernandez,Sonja Scholz,Alisdair McNeill,Rosie Taylor,Li Su,Iain Wilkinson,
BRAINno. 1 (2024): 267-280
Journal of Parkinson's diseaseno. 6 (2023): 853-866
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Wing Hei Au,Leonor Miller-Fleming,Alvaro Sanchez-Martinez, James Lee,Madeleine J Twyning,Hiran Prag, Sarah Granger, Katie Roome,Laura Ferraiuolo,Heather Mortiboys,Alexander J Whitworth
biorxiv(2023)
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Andreas Luxenburger, Hannah Clemmens, Christopher Hastings,Lawrence D. Harris,Elizabeth M. Ure,Scott A. Cameron,Jan Aasly,Oliver Bandmann,Alex Weymouth-Wilson,Richard H. Furneaux,Heather Mortiboys
BIOMOLECULESno. 1 (2023)
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