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Westerhoff moved progressively towards working on multi-enzyme systems as his major activity, starting with an analysis of the effect of enzyme activity on metabolite concentrations. He published many papers in this area, of which one may note an analysis of the control of regulatory cascades, analysqis of glycolytic oscilations in yeast, and showing that the in vivo behaviour of Trypanosoma brucei agreed with the kinetic properties of the glycolytic enzymes.
Westerhoff and colleagues discovered magainin in the African clawed frog which helps it fight against bacteria. In December 1996 he and his group discovered a nitric-oxide reductase of Paracoccus denitrificans.
In conjunction with many other workers Westerhoff used a community approach to construct a consensus yeast metabolic network and subsequently applied the same approach to human metabolism.
Westerhoff and colleagues discovered magainin in the African clawed frog which helps it fight against bacteria. In December 1996 he and his group discovered a nitric-oxide reductase of Paracoccus denitrificans.
In conjunction with many other workers Westerhoff used a community approach to construct a consensus yeast metabolic network and subsequently applied the same approach to human metabolism.
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The EMBO journalno. 23 (2023): e115008-e115008
LIFE-BASELno. 11 (2023): 2120-2120
Bio Systems (2023): 104988-104988
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