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She conducted undergraduate research on growth factor receptor tyrosine kinase-mediated signaling pathways in the laboratory of Hong Wu for three years;Dr. Christofk discovered an important role for the M2 splice isoform of pyruvate kinase (PKM2) in cancer metabolism and tumor growth;She elucidated a novel regulatory mechanism by which tyrosine kinase signaling pathways directly impact metabolism through modulation of PKM2 activity;she studied additional mechanisms of cancer metabolism regulation in the laboratory of Dr. Frank McCormick at UCSF; Her research focus on the interconnection of growth factor signaling pathways and metabolism, with the overarching goals to understand how metabolism is regulated in cancer, and how to target altered metabolism for therapeutic benefit.
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论文共 137 篇作者统计合作学者相似作者
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Lydia Ouchene, Blake Wilde, Fiona Chan-Pak-Choon, Jose Camacho Valenzuela,Fadi Brimo,Leora Witkowski,Heather Christofk,Celine Domecq, Lili Fu,Evan Weber, Brianna Lemieux Anglin,Elena Netchiporouk,
GENES CHROMOSOMES & CANCERno. 2 (2024): e23221-e23221
Sicheng Zhang,Kevin J. Williams, Amandine Verlande-Ferrero,Alvin P. Chan, Gino B. Su,Erin E. Kershaw,James E. Cox,John Alan Maschek,Suzanne N. Shapira,Heather R. Christofk,Thomas Q. de Aguiar Vallim,Selma Masri,
JOURNAL OF LIPID RESEARCHno. 2 (2024): 100434-100434
Hannah L. Sunshine,Andrew C. Cicchetto,Karolina Elzbieta Kaczor-Urbanowicz,Feiyang Ma, Danielle Pi, Chloe Symons,Martin Turner,Vipul Shukla,Heather R. Christofk,Thomas A. Vallim,M. Luisa Iruela-Arispe
CELL REPORTSno. 1 (2024): 113627-113627
Daniel Braas,Ethan Ahler, Brenna Tam,David Nathanson, Mirielle Riedinger,Matthias R. Benz, Kathleen B. Smith,Fritz C. Eilber,Owen N. Witte,William D. Tap,Hong Wu,Heather R. Christofk
crossref(2023)
Kevin J. Williams,Joseph P. Argus,Yue Zhu,Moses Q. Wilks,Beth N. Marbois,Autumn G. York,Yoko Kidani, Alexandra L. Pourzia,David Akhavan,Dominique N. Lisiero,Evangelia Komisopoulou, Amy H. Henkin,
crossref(2023)
Daniel Braas,Ethan Ahler, Brenna Tam,David Nathanson, Mirielle Riedinger,Matthias R. Benz, Kathleen B. Smith,Fritz C. Eilber,Owen N. Witte,William D. Tap,Hong Wu,Heather R. Christofk
crossref(2023)
Journal of Urologyno. Supplement 4 (2023)
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