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The research in our laboratory is focused on determining the molecular pathogenesis of infections and inflammatory diseases. We are interested in two key areas in the pathogenic process; microbial adherence to host tissue and microbial evasion of host defense systems. We seek to identify the molecules involved in these processes, characterize the interactions in submolecular detail using detailed biochemical methods, and articulate molecular hypotheses describing the disease process. These hypotheses are then evaluated in model systems and compared to the clinical findings in human disease. Ultimately, we seek to translate our research findings into new or improved strategies to prevent and treat infectious diseases.
研究兴趣
论文共 449 篇作者统计合作学者相似作者
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Yue Hu, Abhijit Sarkar,Kevin Song, Sara Michael,Magnus Hook,Ruoning Wang,Andras Heczey,Xiaotong Song
Cell Reports Medicinepp.101530-101530, (2024)
Yu Zeng,Michael Woolley,Karuppiah Chockalingam, Benjamin Thomas,Srishtee Arora,Magnus Hook,Zhilei Chen
Nucleic acids research (2023)
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Caishang Zheng,Yanjun Wei,Peng Zhang,Kangyu Lin,Dandan He,Hongqi Teng,Ganiraju Manyam,Zhao Zhang,Wen Liu, Hye Rin Lindsay Lee,Ximing Tang,Wei He,
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Cancer Researchno. 7_Supplement (2023): 4092-4092
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biorxiv(2022)
Cynthia V Pagba,Amit K Gupta,Ali K Naji,Dharini van der Hoeven,Kelly Churion,Xiaowen Liang, Jacob Jakubec,Magnus Hook,Yan Zuo, Marisela Martinez de Kraatz,Jeffrey A Frost,Alemayehu A Gorfe
ACS bio & med chem Auno. 6 (2022): 617-626
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