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Her laboratory research is focused on understanding the dysfunction and loss of synapses that occurs in Alzheimer's disease (AD), and she has pioneered the use of flow cytometry for the analysis of synaptosomes. Her projects use primarily human postmortem AD samples and mouse models of the disease. Research interests include neuroinflammation and APOE risk for AD, the single biggest genetic risk, which can also be also protective. Recent projects have isolated brain cell types from human postmortem samples in order to study microglial and astrocyte effects on AD progression. We also have new projects looking at exosome mechanisms in pathology and signaling between cortical cell types.
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论文共 58 篇作者统计合作学者相似作者
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Mikhail Melnik,Emily Miyoshi, Ricky Ma,Maria Corrada,Claudia Kawas, Ryan Bohannan, Chad Caraway,Carol A Miller,Jason D Hinman,Varghese John,Tina Bilousova,Karen H Gylys
Journal of neuroscience methods (2024): 110137-110137
Mikhail Melnik,Emily Miyoshi, Ricky Ma,Maria Corrada,Claudia Kawas, Ryan Bohannan, Chad Caraway,Carol A. Miller,Jason D. Hinman,Varghese John,Tina Bilousova,Karen H. Gylys
Journal of Neuroscience Methodspp.110137, (2024)
Olivier Landry,Arnaud François, Méryl-Farelle Oye Mintsa Mi-Mba,Marie-Therese Traversy,Cyntia Tremblay,Vincent Emond,David A Bennett,Karen H Gylys,Joseph D Buxbaum,Frederic Calon
The Journal of neuroscience : the official journal of the Society for Neuroscienceno. 26 (2023): 4941-4954
PubMed (2021): e055260-e055260
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Molecular Brainno. 1 (2021): 1-8
Emily Miyoshi,Tina Bilousova,Mikhail Melnik, Danyl Fakhrutdinov,Wayne W. Poon,Harry V. Vinters,Carol A. Miller,Maria Corrada,Claudia Kawas, Ryan Bohannan, Chad Caraway,Chris Elias,
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