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职业迁徙
个人简介
We are interested in the mechanisms of neuroinflammation and neurodegeneration in the brain. We use mouse models of disease and cultured brain cells to investigate how microglia become activated by inflammatory stimuli, and how such microglia can damage or protect neurons. We are particularly interested in the roles of microglial phagocytosis in neurodegeneration, as we have found that inflamed microglia can phagocytose (i.e. eat) live neurons and neuronal parts such as synapses. And so we are trying to find ways to prevent this.
Research objectives
Understand the roles of microglia in neuroinflammation and neurodegeneration.
Determine how to prevent excessive microglial phagocytosis of neurons and synapses in neurodegenerative diseases.
Understand the roles of cell death by phagocytosis in the body and in the brain.
研究兴趣
论文共 305 篇作者统计合作学者相似作者
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iScienceno. 4 (2024): 109454-109454
Frontiers in Aging Neuroscience (2024): 1327756-1327756
Molecular neurodegenerationno. 1 (2024): 30-30
Molecular Neurodegenerationno. 1 (2024): 1-14
Scientific reportsno. 1 (2023): 10813-14
ACTA NEUROPATHOLOGICAno. 4 (2023): 509-510
MOVEMENT DISORDERSno. 7 (2023): 1143-1155
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