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个人简介
I work with development of digital twins: computer models describing cells, organs, and the whole body. These twins are useful for eHealth, drug development, basic research, replacement of animal experiments, and artistic expressions.
My basic training is in theoretical physics, where I have a M.Sc from Linköping university, but since my M.Sc. project I have been working with systems biology. First I went to Copenhagen, to work on the insulin-producing beta cells, and from there to ISY in Linköping for 3 years, and to FCC in Gothenburg for 2 years. During those latter 5 years I did my Ph.D. thesis, which main accomplishment was the development of a new modelling approach: core-box modelling (symbolized by the logo above). Up until then I had only worked in theoretical, typically engineering, groups. After my Ph.D. I returned to Linköping, to build up my own systems biology group, at the experimental department IKE, within the group of Peter Strålfors. During the first 4 years, I was also travelling 2 times a year for 1-2 months visits to various groups in the world: e.g., to Hiroaki Kitano, Stefan Hohmann, Jens Timmer, and Alejandro Colman-Lerner. In 2011, I received a FoAss position from the Swedish Research council, and that allowed me to start building up a more independent modelling group: called Integrative Systems Biology (isbgroup.eu). I have also started the Linköping Centre for Systems Biology (LCSB), and the most active part of this is centered around my group, which also functions as a core facility, currently used by more than 10 other research groups.
My basic training is in theoretical physics, where I have a M.Sc from Linköping university, but since my M.Sc. project I have been working with systems biology. First I went to Copenhagen, to work on the insulin-producing beta cells, and from there to ISY in Linköping for 3 years, and to FCC in Gothenburg for 2 years. During those latter 5 years I did my Ph.D. thesis, which main accomplishment was the development of a new modelling approach: core-box modelling (symbolized by the logo above). Up until then I had only worked in theoretical, typically engineering, groups. After my Ph.D. I returned to Linköping, to build up my own systems biology group, at the experimental department IKE, within the group of Peter Strålfors. During the first 4 years, I was also travelling 2 times a year for 1-2 months visits to various groups in the world: e.g., to Hiroaki Kitano, Stefan Hohmann, Jens Timmer, and Alejandro Colman-Lerner. In 2011, I received a FoAss position from the Swedish Research council, and that allowed me to start building up a more independent modelling group: called Integrative Systems Biology (isbgroup.eu). I have also started the Linköping Centre for Systems Biology (LCSB), and the most active part of this is centered around my group, which also functions as a core facility, currently used by more than 10 other research groups.
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Christian Simonsson,Wolf Claus Bartholoma, Anna Lindhoff-Larsson,Markus Karlsson, Shan Cai, Jens Tellman, Bengt Noren,Bergthor Bjornsson,Gunnar Cedersund,Nils Dahlstrom,Per Sandstrom,Peter Lundberg
medrxiv(2024)
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biorxiv(2023)
BIOCHEMICAL ENGINEERING JOURNAL (2023): 108798
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