Guixue Yu

Discovery Chemistry Drug Metabolism and Pharmacokinetics, Drug Safety, and Metabolic and Cardiovascular Drug Discovery, Bristol-Myers Squibb Pharmaceutical Research Institute

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论文共 26 篇作者统计合作学者相似作者

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Reductions in Log P Improved Protein Binding and Clearance Predictions Enabling the Prospective Design of Cannabinoid Receptor (CB1) Antagonists with Desired Pharmacokinetic Properties

Bruce A. Ellsworth,Philip M. Sher,Ximao Wu,Gang Wu,Richard B. Sulsky,Zhengxiang Gu,Natesan Murugesan,Yeheng Zhu,Guixue Yu,Doree F. Sitkoff,Kenneth E. Carlson,Liya Kang,Yifan Yang,Ning Lee,Rose A. Baska,William J. Keim,Mary Jane Cullen,Anthony V. Azzara,Eva Zuvich,Michael A. Thomas,Kenneth W. Rohrbach,James J. Devenny,Helen E. Godonis,Susan J. Harvey,Brian J. Murphy,Gerry G. Everlof,Paul I. Stetsko,Olafur Gudmundsson,Susan Johnghar,Asoka Ranasinghe,Kamelia Behnia,Mary Ann Pelleymounter,William R. Ewing

Journal of Medicinal Chemistry（2013）

引用10浏览0WOS引用

accumulation and leukocyte infiltration

Liya Kang,Kim W Mcintyre,Kathleen M Gillooly,Yifan Yang,John W Haycock,Stephen Roberts,Ashish Khanna,Timothy F Herpin,Guixue Yu,Ximao Wu,Judy Wardwellswanson,John E Macor,R Michael Lawrence,Kenneth E Carlson

mag（2013）

引用23浏览0引用

Strategies To Reduce Log P To Improve Pharmaceutical Properties Of A Series Of Cb1 Receptor Antagonists

Ximao Wu,Bruce A. Ellsworth,Guixue Yu,Amarendra Mikkilineni,Zhengxiang Gu,Natesan Murugesan,Yanting Huang,Chongqing Sun,Annapurna Pendri,Philip M. Sher,Gang Wu,Yeheng Zhu,Doree F. Sitkoff,Liya Kang,Yifan Yang,Ning Lee,Mary Jane Cullen,William J. Keim,Mary Ann Pelleymounter,Paul I. Stetsko,Gerry G. Everlof,Olafur S. Gudmunsson,Susan Johnghar,Steven T. Wu,Asoka Ranasinghe,Wenying Li,Kamelia Behnia,Kenneth E. Carlson,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2012)

引用0浏览0引用

Design, Synthesis And Sar Of Triazolopyridazine Based Cannabinoid-1 Receptor Antagonists

Yanting Huang,Chongqing Sun,Guixue Yu,Amarendra Mikkilineni,Ximao Wu,Zhengxiang Gu,Natesan Murugesan,Bruce A. Ellsworth,Annapurna Pendri,Philip Sher,Gang Wu,Yeheng Zhu,Doree Sitkoff,Liya Kang,Yifan Yang,Ning Lee,Mary Jane Cullen,William Keim,Mary Ann Pelleymounter,Paul Stetsko,Gerry Everlof,Olafur Gudmunsson,Susan Johnghar,Steven Wu,Asoka Ranasinhe,Wenying Li,Kamelia Behnia,Kenneth E. Carlson,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2011)

引用0浏览0引用

Discovery Of Bms-812204, A Cannabinoid Receptor (Cb1) Antagonist, Via Reductions In Log P In The Series To Balance Volume Of Distribution And Clearance

Bruce A. Ellsworth,Ximao Wu,Philip M. Sher,Gang Wu,Amarendra Mikkilineni,Zhengxiang Gu,Natesan Murugesan,Yeheng Zhu,Guixue Yu,Doree Sitkoff,Kenneth Carlson,Liya Kang,Yifan Yang,Ning Lee,Roseann Baska,Qi Huang,William Keim,Mary Jane Cullen,Eva Zuvich,Michael Thomas,Kenneth W. Rohrbach,James J. Devenny,Helen Godonis,Susan Harvey,Brian J. Murphy, Gerry Everloff,Paul Stetsko,Olafur Gudmundsson,Susan Johnghar,Asoka Ranasinghe,Kamelia Behnia,Maryann Pelleymounter,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2009）

引用1浏览0引用

Triazolopyridazines (Tzp) As Cannabinoid-1 Receptor Antagonists: The Generation Of Multiple Novel Tzp Chemotypes Via Conformationally Constraining A Pyrazine Carboxamide Lead

Chongqing Sun,Yanting Huang,Guixue Yu,Amarendra Mikkilineni,Ximao Wu,Zhengxiang Gu,Natesan Murugesan,Bruce A. Ellsworth,Philip Sher,Annapurna Pendri,Gang Wu,Yeheng Zhu,Samuel Gerritz,Doree Sitkoff,Liya Kang,Yifan Yang,Rose Ann Baska,Ning Lee,Mary Jane Cullen,William Keim,Mary Ann Pelleymounter,Paul Stetsko,Gerry Everlof,Susan Johnghar,Steven Wu,Asoka Ranasinhe,Wenying Li,Kamelia Behnia,Kenneth E. Carlson,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2009）

引用0浏览0引用

Medi 462-Balancing Cardiac Liabilities And Pk Properties: Discovery Of Triazolopyridine Based Growth Hormone Secretagogues

Jun Li,Stephanie Y. Chen,Guixue Yu,Amarendra B. Mikklineni,Ximao Wu,Yeheng Zhu,James J. Li,Haixia Wang,Richard B. Sulsky,Shiwei Tao,Andres S. Hernandez,Dorothy Slusarchyk,Ramakrishna Seethala,Mujing Yan,Neil Flynn,Brian J. Murphy,Paul Sleph,Donald Egan,Aberra Fura,Viral Vyas,Kamelia Behnia,James Smalley,Danshi Li,Mary Lee Conder,Huabin Sun,Lucy Sun,Paul C. Levesque,Mary Ellen Salyan,Michael A. Blanar,Robert Zahler,William R. Ewing,David Gordon,Joseph A. Tino

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2008）

引用0浏览0引用

Medi 10-Discovery Of Di-Aryl Triazolopyridazine Cannabinoid Receptor (Cb1) Antagonists

Guixue Yu,Bruce A. Ellsworth,Amarendra Mikkilineni,Ximao Wu,Ying Wang,Doree Sitkoff,Zhengxiang Gu,Natesan Murugesan,Steve Swartz,Kenneth Carlson,Liya Kang,Yifan Yang,Ning Lee,Roseann Baska,Qi Huang,Mary Jane Cullen,Eva Zuvich,Michael Thomas,Kenneth W. Rohrbach, James Devenney,Helen Godonis,Susan Harvey,Susan Johnghar,Kamelia Behnia,Maryann Pelleymounter,William R. Ewing

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2008）

引用0浏览0引用

Medi 461-Discovery Of A Novel, Potent Growth Hormone Secretagogue Receptor Agonist Bms-604992

Jun Li,Stephanie Y. Chen,Guixue Yu,Amarendra B. Mikklineni,Ximao Wu,Richard B. Sulsky,Andres S. Hernandez,James J. Li,Yeheng Zhu,Haixia Wang,Shiwei Tao,Jung-Hui Sun,Leslie Leith,Arvind Mathur,Bang-Chi Chen,Dorothy Slusarchyk,Ramakrishna Seethala, Mujing Yang,Neil Flynn,Brian J. Murphy,Paul Sleph,Donald Egan,Aberra Fura,Viral Vyas,Kamelia Behnia,James Smalley,Danshi Li,Mary Lee Conder,Huabin Sun,Lucy Sun,Paul Levesque,Yi-Xin Li,Mary Ellen Salyan, Ronald West, Mandar Dali,Michael A. Blanar,Robert Zahler,Elizabeth Govek, Ken Longo,Peter S. Distefano,Brad J. Geddes,William R. Ewing,David A. Gordon,Joseph A. Tino

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2008）

引用0浏览0引用

Quinoline inhibitors of cGMP phosphodiesterase

Yingzhi Bi,Guixue Yu,David P Rotella,John E Macor

mag（2007）

引用24浏览0引用

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作者统计

#Papers: 26

#Citation: 514

H-Index: 14

G-Index: 16

Sociability: 5

Diversity: 2

Activity: 0

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