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个人简介
My lab studies how genetic variation predisposes individuals to develop cardiovascular (e.g. myocardial infarction) and hematological (e.g. sickle cell disease) diseases, or how the same genetic variation modulates disease severity. We use modern genetic and genomic approaches, such as genome-wide association studies and next-generation DNA re-sequencing, to identify genetic risk factors for these diseases. Projects in the lab could involve: (1) analyzing complex genetic datasets, (2) developing new algorithm for data mining and integration, and (3) molecular and cellular functional validation of new genetic discoveries.
研究兴趣
论文共 193 篇作者统计合作学者相似作者
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Jayoung Ryu, Sam Barkal,Tian Yu,Martin Jankowiak,Yunzhuo Zhou, Matthew Francoeur,Quang Vinh Phan, Zhijian Li,Manuel Tognon, Lara Brown,Michael I Love, Vineel Bhat,
Jayoung Ryu, Sam Barkal,Tian Yu,Martin Jankowiak,Yunzhuo Zhou, Matthew Francoeur,Quang Vinh Phan, Zhijian Li,Manuel Tognon, Lara Brown,Michael I Love,Guillaume Lettre,
medRxiv : the preprint server for health sciences (2023)
ISCIENCEno. 12 (2023): 108473-108473
Estelle Lecluze,Guillaume Lettre
CANADIAN JOURNAL OF CARDIOLOGYno. 12 (2023): 1888-1897
Scientific reportsno. 1 (2023): 3924-10
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Marisa C. Hamilton,James D. Fife,Ersin Akinci,Tian Yu,Benyapa Khowpinitchai,Minsun Cha,Sammy Barkal, Thi Tun Thi,Grace H. T. Yeo, Juan Pablo Ramos Barroso, Matthew Jake Francoeur,Minja Velimirovic,
CELL GENOMICSno. 5 (2023): 100304-100304
Mehrzad Mehdizadeh, F. Leblanc,Patrice Naud, Yasemin Altuntaş,Éric Thorin,Gerardo Ferbeyre,Jean‐Claude Tardif,Martin G. Sirois,Jean‐François Tanguay,Guillaume Lettre,Stanley Nattel
Circulationno. Suppl_1 (2023)
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