Giovanni Cazzaniga

MAJOR RESEARCH INTERESTS - Genetic predisposition to leukemia - Personalized Medicine in Pediatric Hemato-Oncology - Prenatal origin of leukemia and clonal evolution. - Molecular characterization of childhood ALL and AML. - Minimal residual disease monitoring in childhood ALL, by analysis of T-cell Receptor and Immunoglobulin genes’ rearrangements and fusion gene transcripts. - Functional analysis of genetic aberrations in leukemic patients (PAX5 lesions, Ph-like ALL, Down Syndrome ALL, MLLr)