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Using the fruit fly Drosophila melanogaster, he discovered that epigenetic inheritance of new phenotypes can occur independently on changes of the DNA sequence. His lab also discovered that the three-dimensional organisation of chromosomes in the cell nucleus is a heritable trait that plays an important gene regulatory role. The Cavalli lab identified 3D structural chromosomal domains dubbed Topologically Associating Domains or TADs. Finally, the Cavalli lab has shown that PcG proteins have tumor suppression activity in flies. Giacomo Cavalli has published more than 120 papers, cited over 16,000 times and many of which in top journals. He received numerous awards and distinctions, including an EMBO membership, the CNRS silver medal, the Allianz Foundation price, the Grand Prix 2020 of the Fondation pour la Recherche Médicale and two advanced ERC grants.
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论文共 184 篇作者统计合作学者相似作者
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Chetan C. Rawal,Vincent Loubiere, Nadejda L. Butova, Juliette Garcia, Victoria Parreno,Anne-Marie Martinez,Giacomo Cavalli,Irene Chiolo
crossref(2024)
Emmanuel Varlet,Elina Alaterre, Morgane Thomas, Hugues De Boussac,Laure Vincent,Guillaume Cartron,Charles Herbaux,Caroline Bret,Laurie Herviou,Anne Marie Martinez,Christophe Hirtz,Aurore Attina,
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2023)
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biorxiv(2023)
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Leukemiano. 9 (2023): 1925-1928
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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