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个人简介
The Skiniotis laboratory seeks to resolve structural and mechanistic questions underlying biological processes that are central to cellular physiology. Our investigations employ primarily cryo-electron microscopy (cryoEM) and 3D reconstruction techniques complemented by biochemistry, biophysics and simulation methods to obtain a dynamic view into the macromolecular complexes carrying out these processes. The main theme in the lab is the structural biology of cell surface receptors that mediate intracellular signaling and communication. Our current main focus is the exploration of the mechanisms responsible for transmembrane signal instigation in cytokine receptors and G protein coupled receptor (GPCR) complexes.
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论文共 171 篇作者统计合作学者相似作者
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Fangyu Liu,Cheng-Guo Wu,Chia-Ling Tu, Isabella Glenn,Justin Meyerowitz, Anat Levit Kaplan,Jiankun Lyu,Zhiqiang Cheng, Olga O. Tarkhanova,Yurii S. Moroz,John J. Irwin,Wenhan Chang,
biorxiv(2024)
Feng He,Cheng-Guo Wu,Yang Gao, Sabrina N. Rahman, Magda Zaoralova,Makaia M. Papasergi-Scott,Ting-Jia Gu,Michael J. Robertson,Alpay B. Seven,Lingjun Li,Jesper M. Mathiesen,Georgios Skiniotis
NATUREno. 8001 (2024): 1141-1148
Jiankun Lyu,Nicholas Kapolka,Ryan Gumpper,Assaf Alon,Liang Wang, Manish K Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim,Jeffrey DiBerto,Kuglae Kim,Tia A Tummino,
bioRxiv : the preprint server for biology (2024)
biorxiv(2024)
Feng He,Cheng-Guo Wu,Yang Gao, Sabrina N. Rahman, Magda Zaoralová,Makaía M. Papasergi-Scott,Ting-Jia Gu,Michael J. Robertson,Alpay B. Seven,Lingjun Li,Jesper M. Mathiesen,Georgios Skiniotis
Fangyu Liu,Cheng-Guo Wu,Chia-Ling Tu, Isabella Glenn,Justin Meyerowitz, Anat Levit Kaplan,Jiankun Lyu,Zhiqiang Cheng, Olga O Tarkhanova,Yurii S Moroz,John J Irwin,Wenhan Chang,
bioRxiv : the preprint server for biology (2024)
Structure (London, England : 1993)no. 5 (2023): 553-564.e7
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