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My research interest is on the mechanisms of inflammation and oxidative stress in the liver and carotid bodies. Currently, my work concentrates on the role of antioxidants from herbs and multi-functional drugs M30 on inflammation and oxidative stress in liver diseases, particularly in non-alcoholic liver disease (NAFLD). NAFLD is one of the leading causes of chronic liver injury across the world. It is also strongly related to other pathological conditions, including obesity, diabetes, cardiovascular diseases, and symptoms of metabolic syndrome. Pathogenesis of NAFLD remains not fully characterized but is generally attributed to the occurrence of insulin resistance, lipid metabolism dysfunction, oxidative stress, inflammation, and necro-apoptosis. Every potential therapeutic strategy should target one or some of these pathological events in the liver. Over the past decades, application of herbal treatment for NAFLD received increasing attentions due to its wide availability, low side effects, and proven therapeutic mechanisms and benefits.
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Medical education onlineno. 1 (2023): 2217549-2217549
Fraide Ganotice Jr,Binbin Zheng,Pauline Yeung Ng, Siu Chung Leung, Elizabeth Ann Barrett,Hoi Yan Celia Chan, Chad W. N. Chan,Kit Wa Sherry Chan,Linda Chan,M. K. Karen Chan,Siu Ling Polly Chan, So Ching Sarah Chan,
Advances in physiology educationno. 3 (2023): 594-603
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Anatomical sciences educationno. 6 (2023): 1209-1217
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