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个人简介
Dr. Weiner's research focuses on understanding the mechanisms of action of anti-cancer monoclonal antibodies, and on development of novel approaches to immunotherapy of lymphoma. He has been continually funded by the NCI since 1991 and has been the PI on the University of Iowa / Mayo Clinic Lymphoma Specialized Program of Research Excellence (P50 CA097274) since it was initiated in 2002. This grant was renewed competitively in 2007 and 2012. Dr. Weiner's research extends from basic laboratory investigation to clinical trials. He was the first to demonstrate Toll Like Receptor 9 agonists could be used successfully as immune adjuvants in tumor immunization. He has made major contributions to our understanding of the mechanisms of action responsible for the anti-tumor activity of monoclonal antibodies, including providing evidence that, in some cases, complement can inhibit the efficacy of some monoclonal antibodies. He has established a number of collaborative research programs, including working with Dr. Aliasger Salem from the UI College of Pharmacy on novel uses of nanoparticles to enhance the anti-tumor immune response.
研究兴趣
论文共 363 篇作者统计合作学者相似作者
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Jyoti Arora, Sabarish Ayyappan,Chaobo Yin,Brian J. Smith,Caitlin D. Lemke-Miltner,Zhaoming Wang,Umar Farooq,George J. Weiner
Blood (2024)
Ahmad A. Tarhini, Islam Eljilany, Sam Coleman, Dale J. Hedges,Martin McCarter,John Carpten,Howard Colman,Abdul Rafeh Naqash,Igor Puzanov,Susanne Arnold, Michelle Churchman,Patrick Hwu,
Cancer Researchno. 6_Supplement (2024): 71-71
Alyssa Obermayer,Timothy Shaw,Darwin Chang, Joshua Davis,Jamie K. Teer,Xiaoqing Yu,Xuefeng Wang, Dale Hedges,Aik Choon Tan, Robert Rounbehler,Abdul Rafeh Naqash, Margaret Gatti-Mays,
Cancer Researchno. 6_Supplement (2024): 3886-3886
AMERICAN JOURNAL OF HEMATOLOGYno. 3 (2024): 408-421
Regular and Young Investigator Award Abstracts (2023)
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Journal for ImmunoTherapy of Cancerno. 12 (2023)
CANCER RESEARCHno. 7 (2023)
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Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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Sarah H Nash,Charles F Lynch,Michele M West,Amanda R Kahl, Daniel B Olson,Natoshia M Askelson,George Weiner, Suzanne E Bentler,Mary E Charlton
crossref(2023)
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