基本信息
浏览量:145
职业迁徙
个人简介
Research interests
Leader: Cardiac
The compartmentalisation of PDE4 isoforms and how this underpins receptor specific responses to Beta-adrenergic signalling.
The post-translational modification of cardiac signalling proteins during disease.
The turnover of cardiac cAMP signalling proteins by the Ubiquitin proteosome.
Inhibition of protein-protein interactions as a therapeutic strategy in disease.
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
CiC New Treatments for Heart Failure with Preserved Ejection Fraction (HFpEF)
Medical Research Council
2017 - 2018
CiC Enhancing Mas:ETB receptor interaction: A novel therapeutic modality for pulmonary hypertension.
Medical Research Council
2016 - 2018
Regulation of Anti-inflammatory Gene Expression in Vascular Endothelial Cells by EPAC1
British Heart Foundation
2015 - 2018
Validation of the PDE4D7 interactome
Prostate Cancer UK
2015 - 2016
Pathway-driven identification of therapeutic targets for combating Alzheimer's disease.
Medical Research Council
2015 - 2018
Accumulation of novel information cncerning the cell signalling pathways underpinning colorectal cancer, as well as possible new treatments
The Great Britain Sasakawa Foundation
2015 - 2018
P2D award - GRACE II - PPL/SANNOX discussion with external advisors: targets and therapeutic indications
Medical Research Council
2015 - 2017
CiC: Small molecules targeting the PDE4A4-p75NTR interaction, a novel target for fibrotic diseases
Medical Research Council
2014 - 2015
Extracellular signal-regulated kinase 5 (ERK5) and regulation of neuroendocrine differentiation in prostate cancer
Chief Scientist Office
2012 - 2014
cAMP phosphodiesterase-4: signalling complexes, regulation and potential therapeutic targets.
Medical Research Council
2012 - 2015
Small molecules that induce the cardio-protective effects of HSP20
Heart Research UK
2012 - 2014
Disrupting arresting binding partners to influence cell shape and mobility
The Royal Society
2011 - 2013
Phosphodiesterase-4 isoforms - intracellular targeting, regulation and potential therapeutic targets
Medical Research Council
2007 - 2012
Transatlantic networks of excellence in cardiovascular disease
Fondation Leducq
2006 - 2012
Leader: Cardiac
The compartmentalisation of PDE4 isoforms and how this underpins receptor specific responses to Beta-adrenergic signalling.
The post-translational modification of cardiac signalling proteins during disease.
The turnover of cardiac cAMP signalling proteins by the Ubiquitin proteosome.
Inhibition of protein-protein interactions as a therapeutic strategy in disease.
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
CiC New Treatments for Heart Failure with Preserved Ejection Fraction (HFpEF)
Medical Research Council
2017 - 2018
CiC Enhancing Mas:ETB receptor interaction: A novel therapeutic modality for pulmonary hypertension.
Medical Research Council
2016 - 2018
Regulation of Anti-inflammatory Gene Expression in Vascular Endothelial Cells by EPAC1
British Heart Foundation
2015 - 2018
Validation of the PDE4D7 interactome
Prostate Cancer UK
2015 - 2016
Pathway-driven identification of therapeutic targets for combating Alzheimer's disease.
Medical Research Council
2015 - 2018
Accumulation of novel information cncerning the cell signalling pathways underpinning colorectal cancer, as well as possible new treatments
The Great Britain Sasakawa Foundation
2015 - 2018
P2D award - GRACE II - PPL/SANNOX discussion with external advisors: targets and therapeutic indications
Medical Research Council
2015 - 2017
CiC: Small molecules targeting the PDE4A4-p75NTR interaction, a novel target for fibrotic diseases
Medical Research Council
2014 - 2015
Extracellular signal-regulated kinase 5 (ERK5) and regulation of neuroendocrine differentiation in prostate cancer
Chief Scientist Office
2012 - 2014
cAMP phosphodiesterase-4: signalling complexes, regulation and potential therapeutic targets.
Medical Research Council
2012 - 2015
Small molecules that induce the cardio-protective effects of HSP20
Heart Research UK
2012 - 2014
Disrupting arresting binding partners to influence cell shape and mobility
The Royal Society
2011 - 2013
Phosphodiesterase-4 isoforms - intracellular targeting, regulation and potential therapeutic targets
Medical Research Council
2007 - 2012
Transatlantic networks of excellence in cardiovascular disease
Fondation Leducq
2006 - 2012
研究兴趣
论文共 317 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
MOLECULAR ONCOLOGYno. 3 (2024): 707-725
Sean F Cooke, Thomas A Wright,Yuan Yan Sin,Jiayue Ling, Elka Kyurkchieva,Nattaporn Phanthaphol, Thomas Mcskimming, Katharine Herbert,Selma Rebus,Andrew V Biankin,David K Chang,George S Baillie,
Meghan Sedovy, David King,Xinyan Leng, Arya Malek,George Baillie, Joseph W. Baker,Mark Joseph,James W. Smyth,Brant E. Isakson,Scott R. Johnstone
British journal of cancerno. 9 (2023): 1462-1476
引用0浏览0WOSNATURE引用
0
0
crossref(2023)
BIOCHEMICAL JOURNALno. 20 (2023): 1599-1614
引用0浏览0WOS引用
0
0
The international journal of biochemistry & cell biology (2023): 106453-106453
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Frontiers in bioscience (Landmark edition)no. 7 (2023): 133-133
Meghan W. Sedovy, Dennis King,Xinyan Leng, Anastasia Malek,George S. Baillie,Joseph W. Baker,Mark Joseph, J. D. Smyth,Brant E. Isakson,Scott R. Johnstone
Arteriosclerosis, Thrombosis, and Vascular Biologyno. Suppl_1 (2023)
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn