基本信息
浏览量:210
职业迁徙
个人简介
I conduct clinical research on a variety of gastrointestinal cancers and provide care for patients with those cancers. We have trials of combined modality therapy (surgery +/- radiation +/- chemotherapy) on gastric, esophageal, pancreas and rectal cancers. We also perform phase I and II trials of biologically targeted agents as well as newer immunotherapeutics. In collaboration with a number of colleagues, we conduct translational studies analyzing novel imaging (e.g. contrast enhanced ultrasound and perfusion scans) and molecular biomarkers (e.g. CDX2 as a prognostic and predictive factor in colon cancer and matrix metalloproteinases as prognostic factors in pancreas cancer). Neuroendocrine tumors, pancreas, colorectal and gastro-esophageal cancers have been areas of particular research focus with multiple therapeutic and translational studies devote to each. Examples of recently completed trials include a randomized phase III trial of a vaccine (algenpantucel) for resected pancreas cancer, phase Ib trial of anti-PD-L1 and separate phase II trials using PD-1 antibody for tumors with micro satellite instability and chemotherapy with angiogenesis inhibitors for advanced neuroendocrine tumors and gastro-esophageal adenocarcinomas. Currently active areas of study include combining immunomodulating antibodies in combination therapy and randomized phase II colon cancer trials of an antibody to interleukin 1 or a first in class agent known as RadioRx. Participation and leadership in NCI cooperative group protocols gives our patients access to the randomized trials that hope to establish new standards of care for a variety of GI cancers.
研究兴趣
论文共 307 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Jeanne Shen,Yoon-La Choi,Taebum Lee,Hyojin Kim,Young Kwang Chae,Ben W Dulken, Stephanie Bogdan, Maggie Huang,George A Fisher,Sehhoon Park,Se-Hoon Lee, Jun-Eul Hwang,
Journal for ImmunoTherapy of Cancerno. 2 (2024)
Caressa Hui,Agnes Ewongwo,Brianna Lau,George Fisher,Daniel Delitto,George Poultsides, Quoc-Anh Ho,Elham Rahimy,Erqi Pollom,Daniel T Chang, Lucas K Vitzthum
Annals of surgical oncologyno. 2 (2024): 817-817
Caressa Hui, Agnes Ewongwo,Brianna Lau,George Fisher,Daniel Delitto,George Poultsides, Quoc-Anh Ho,Elham Rahimy,Erqi Pollom,Daniel T. Chang,Lucas K. Vitzthum
Annals of surgical oncologyno. 2 (2024): 817-817
引用1浏览0WOS引用
1
0
Cureusno. 9 (2023)
引用0浏览0WOS引用
0
0
JAMA network openno. 11 (2023)
Endocrine Abstracts (2023)
引用0浏览0引用
0
0
Jaclyn P. Lyman,Christopher R. Cabanski, Stephen Maddock,Robert A. Wolff,Zev A. Wainberg,Andrew H. Ko,Osama E. Rahma,George A. Fisher,Peter Edward Gabriel,Abigail Doucette,Binbin Zheng-Lin, Molly A. Maloy,
JOURNAL OF CLINICAL ONCOLOGYno. 4_suppl (2023): 757-757
引用0浏览0引用
0
0
American Journal of Clinical Oncology (2023)
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn