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He is a physician-scientist whose work has been funded by the National Science Foundation, National Institute of Health, Department of Veterans Affairs, American Heart Association, and the Robert Wood Johnson foundation. His major contributions to science include the discovery a specific voltage-gated potassium channel that regulates body weight and insulin sensitivity, and the identification of a new growth factor, which he named renalase. He elucidated the pathway through which renalase affects cellular signaling and discovered that the protein can function abnormally and facilitate the development of certain cancers. Hi laboratory is currently focused on developing drugs that can treat cancer by blocking the action of renalase in cancer cells. Dr. Desir is a named inventor on several patents related to the discovery and therapeutic use of renalase, and the development of drugs that modulate renalase signaling in cancer. He is the scientific founder of 2 biotechnology companies focused on developing renalase-based therapies.
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论文共 82 篇作者统计合作学者相似作者
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Journal of Biotechnology and Biomedicineno. 01 (2024)
Research square (2024)
Journal of Hypertensionno. Suppl 1 (2024)
Xiaojia Guo,Heino Velazquez, Leyuan Xu, Zhongshan Cheng, Tian-Min Chen, Yuan Tian, Joerg Bewersdorf,Valerie Blanc,Nicholas Davidson,Robert L. Safirstein,Gary V. Desir
Journal of the American Society of Nephrologyno. 11S (2023): 451-451
medrxiv(2023)
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medRxiv (Cold Spring Harbor Laboratory) (2023)
Lindsay Hollander,Xiaojia Guo,Heino Velazquez, John Chang,Robert Safirstein,Harriet Kluger,Charles Cha,Gary V. Desir
crossref(2023)
Scientific reportsno. 1 (2023): 22255-22255
Journal of the American Society of Nephrologyno. 11S (2023): 117-117
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