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My research over the past decade has had two closely related aims: firstly, to elucidate the mechanisms of diabetic organ damage; secondly, to determine the metabolic basis of age-related dementia, starting with Alzheimer's Disease and Huntington's Disease and continuing with Parkinson's disease dementia and vascular dementia; and finally to use diabetic organ damage (particularly neurodegeneration) as a 'Rosetta Stone' to find mechanistically relevant perturbations that might be shared among them. This approach is based on epidemiological evidence and molecular data linking diabetes with common age-related dementias.
I was elected a Fellow of the Royal Society of New Zealand in 1998 and a Fellow of the Academy of Medical Sciences (UK) in 2013.
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EBioMedicine (2023): 104824-104824
Frontiers in molecular neuroscience (2023): 1215637
crossref(2023)
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