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Dr. Tigyi's research is aimed at elucidating the structure and function as well as the signal transduction mechanism of a family of endogenous phospholipids with growth factor-like properties. Dr. Tigyi has shown that serum contains a set of lipid factors that are the major source of mitogenic stimuli present in serum. The best characterized member of this group of lipid mediators is lysophosphatidic acid (LPA). Dr. Tigyi's group has identified the PSP24 receptor gene for LPA and has determined the ligand binding pocket for the EDG family of sphingosine-1-phosphate receptors and LPA receptors. Dr. Tigyi's group has made pioneering contributions to the current understanding of the pharmacology of phospholipid growth factors.
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论文共 365 篇作者统计合作学者相似作者
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JOURNAL OF CELLULAR PHYSIOLOGYno. 1 (2024): 112-123
International Journal of Molecular Sciencesno. 8375 (2023): 8375-8375
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crossref(2023)
The FASEB Journalno. 7 (2023)
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Pradeep K Shukla,Roshan G Rao,Avtar S Meena,Francesco Giorgianni,Sue Chin Lee, Preeti Raju,Nitesh Shashikanth, Chandra Shekhar, Sarka Beranova,Louisa Balazs,Gabor Tigyi,Ankush Gosain,
Journal of dental sciencesno. 3 (2023): 1219-1226
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Acta Pharmacologica Sinicano. 2 (2023): 1-15
FASEB journal : official publication of the Federation of American Societies for Experimental Biologyno. 7 (2023)
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Anna Janovicz, Aliz Majer, Mónika Kosztelnik,Miklós Geiszt, Jerold Chun,Satoshi Ishii,Gábor József Tigyi,Zoltán Benyó,Éva Ruisanchez
Experimental biology and medicine (Maywood, N.J.)no. 20 (2023): 1887-1894
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