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The Center for Metabolomics is developing mass spectrometry-based technologies to create a better understanding of metabolism. These developments include nanostructure-based imaging, cloud-based informatics, as well as a unique database to facilitate metabolite identification. Our XCMS-METLIN platform has thousands of users in over 100 different countries, and our imaging approach is a novel matrix-free technology. Overall, the primary motivation from the outset of our 30+ years at Scripps, is in identifying endogenous metabolites that modulate phenotype. These studies have made me acutely aware of the power of metabolites to understand and control disease pathogenesis.
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Erin S. Baker, Winnie Uritboonthai, Aries Aisporna, Corey Hoang,Heino M. Heyman,Lisa Connell, Damien Olivier-Jimenez,Martin Giera,Gary Siuzdak
Nature Metabolismpp.1-2, (2024)
Analytical chemistry (2024)
Corey Hoang,Winnie Uritboonthai,Linh Hoang,Elizabeth M. Billings,Aries Aisporna, Farshad A. Nia,Rico J. E. Derks,James R. Williamson,Martin Giera,Gary Siuzdak
ANALYTICAL CHEMISTRYno. 14 (2024): 5478-5488
Cell chemical biologyno. 9 (2023): 1115-1134.e10
CELL CHEMICAL BIOLOGYno. 9 (2023): 1115-+
Nature methodsno. 12 (2023): 1836-1837
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