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Our cells are instructed on how to behave by a large number of external signals, which come from contact with neighboring cells, from signaling molecules that enter the circulation from elsewhere in the body to affect distant cells, and from signaling molecules that alert us to the presence of invading organisms (viruses, bacteria, fungi, parasites). The signals are conveyed from the outside of the cell to the inside by specialized receptors on the cell surface. Responses to signals result in changes in cellular functions, for example, by increasing the level of antiviral proteins in response to an infection. These changes are carried out by increasing the amounts of specific proteins or by changing their properties. We study the details of these complex interactions in innate immunity and in cancer.
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Kala K Mahen, Lilian Markley,Jolie Bogart, Hope Klatka,Vijay Krishna,Edward V Maytin,George R Stark,Christine McDonald
Experimental dermatologyno. 9 (2023): 1485-1497
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Tao Lu,George R. Stark
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Kala K Mahen, Laura A. Markley, J.A. Bogart, Hope Klatka,Vijay Krishna,Edward V. Maytin,George R. Stark,Christine McDonald
Experimental Dermatologyno. 9 (2023): 1485-1497
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