Dr. George Hripcsak, MD, MS, is interested in the clinical information stored in electronic health records and in the development of next-generation health record systems. Health record data are sparse, irregularly sampled, complex, and biased. Using nonlinear time series analysis methods borrowed from statistical physics, machine learning, knowledge engineering, and natural language processing, he is developing the methods necessary to support clinical research and patient safety initiatives using health record data. Dr. Hripcsak also has a long track record of developing, implementing, and studying informatics interventions to improve health care. He has published frequently on evaluation in biomedical informatics, leveraging his training in biostatistics.