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My laboratory is focused on three related questions: How is the enormous diversity of local GABAergic inhibitory neurons within the cerebral cortex created? How do each of the unique interneuron subtypes become seamlessly integrated into the brain during development? How does this diversity contribute to canonical excitatory/inhibitory circuits that ultimately shape mammalian brain activity? A century ago Ramon y Cajal dubbed these inhibitory interneurons,“the butterflies of the soul.” With characteristic insight, he inferred that these populations, which possess such enormous morphological diversity, would ultimately prove to have an equally impressive breadth of functional attributes. Recent studies have borne out this prediction and shown that inhibitory interneurons are much more than simple gatekeepers of excitation. Depending on which interneuron subtype is recruited, they are able to refine or unite brain activity in a startling multitude of ways.
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论文共 238 篇作者统计合作学者相似作者
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NEURONno. 2 (2024): 184-200
bioRxiv : the preprint server for biology (2024)
biorxiv(2024)
Deepanjali Dwivedi, Dimitri Dumontier,Mia Sherer,Sherry Lin,Andrea Mc Mirow,Yanjie Qiu,Qing Xu, Samuel A Liebman, Djeckby Joseph,Sandeep R Datta,Gord Fishell,Gabrielle Pouchelon
bioRxiv : the preprint server for biology (2024)
Yating Wang,Deepanjali Dwivedi, Min Dai, Elisabetta Furlanis,Josselyn Vergara, Brenda Leyva, Sarah Du, Rohan Badiani, Aniqa Tarafdar, Justin McMahon,Bram Gorissen,Jordane Dimidschstein,
MOLECULAR THERAPYno. 4 (2023): 227-227
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biorxiv(2023)
Social Science Research Networkno. 17 (2022): 2675-2692.e9
Cell Reports Methodsno. 6 (2022): 100225-100225
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