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Vaccines and antivirals are the primary strategies used to combat viral infections in humans and emerging pandemics. HIV-1, influenza and more recently, the emergence of Zika and SARS-CoV-2, pose significant challenges. For HIV-1, infected individuals harbor a substantial array of HIV-1 variants, a situation that presents a daunting challenge for developing vaccines and therapies. Similarly, the worldwide variability in flu reservoirs makes it difficult to predict which flu strain might acquire the ability to infect the human population, and due to the narrow timeframe between detecting a human infection and the “predict and produce” method for generating the vaccine each season, current influenza vaccines will likely be inadequate for preventing the next flu pandemic. Furthermore, transmission of viruses form mosquitos, such as Zika or from animals, such as SAR-CoV-2 pose a constant threat and new vaccine and antiviral technologies capable or rapidly responding to these threats are urgently needed. In an effort to address these issues, we are investigating new vaccine and antiviral concepts aimed at achieving broader, more universal protection against a wider range of highly variable viruses.
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论文共 174 篇作者统计合作学者相似作者
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Alexander A Cohen,Jennifer R Keeffe,Ariën Schiepers,Sandra E Dross,Allison J Greaney, Annie V Rorick,Han Gao,Priyanthi N P Gnanapragasam,Chengcheng Fan,Anthony P West, Arlene I Ramsingh, Jesse H Erasmus,
bioRxiv : the preprint server for biology (2024)
JOURNAL OF MEDICAL PRIMATOLOGYno. 5 (2023): 339-339
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Sandra E. Dross,Megan N. Fredericks, Mathias D. Maughan,Justin T. Ulrich-Lewis,Thomas B. Lewis, Sarah B. Jones,James T. Fuller,Solomon Wangari, Arlene I. Ramsingh,Janice Pata,Jesse Erasmus,Kenneth C. Bagley,
JOURNAL OF MEDICAL PRIMATOLOGYno. 5 (2023): 342-342
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Frontiers in immunology (2023): 1188018
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Charlene Miller,Jennifer A. Manuzak,Andrew T. Gustin, Christopher M. Basting,Ryan Cheu, Timm Schroeder, Ana Velez,Connor B. Driscoll,Jennifer Tisoncik-Go,Luca Schifanella,Tiffany Hensley-McBain, Claudya A. Evandy,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Frontiers in Virology (2023)
JOURNAL OF MEDICAL PRIMATOLOGYno. 5 (2023): 311-312
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JOURNAL OF MEDICAL PRIMATOLOGYno. 5 (2023): 328-329
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JOURNAL OF MEDICAL PRIMATOLOGYno. 5 (2023): 341-341
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